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Article: A critical period for nicotine-induced disruption of synaptic development in rat auditory cortex.

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Aramakis VB; Hsieh CY; Leslie FM; Metherate R
J. Neurosci., 2000


Table 4.

Nicotine inhibition of α-BTX binding in auditory cortex of rats treated from P8-12 with saline or nicotine (CNE)

4 μm nicotine 40 μm nicotine
Saline CNE Saline CNE
P13 8.0  ± 2.0 11.5  ± 1.8 56.9  ± 8.6 53.9  ± 3.7
P23 25.9  ± 2.9 25.9  ± 1.5 66.6  ± 2.6 71.3  ± 1.7
  • Data are percentage inhibition (mean ± SEM) for four animals in each group. Data across layers did not differ significantly and are averaged. No significant differences between CNE and saline groups.


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