|
Article: Testing the disinhibition hypothesis of epileptogenesis in vivo and during spontaneous seizures.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Buckmaster PS; Jongen-Rêlo AL; Davari SB; Wong EH J. Neurosci., 2000
Table 2.
Intrinsic electrophysiology and inhibitory postsynaptic potentials of granule cells in seizure-resistant and seizure-sensitive gerbils
| Seizure- resistant | Seizure- sensitive | |
|---|---|---|
| n(gerbils) | 12 | 11 |
| Intrinsic electrophysiology | ||
| Resting membrane potential (mV) | −77 ± 2 | −76 ± 2 |
| Input resistance (MΩ) | 84 ± 8 | 72 ± 12 |
| Action potential amplitude (mV) | 73 ± 2 | 75 ± 3 |
| Inhibitory postsynaptic potentials | ||
| Fast (20 msec latency) | ||
| Conductance (nS) | 21 ± 5 | 22 ± 3 |
| Reversal potential (mV) | −67 ± 2 | −69 ± 1 |
| Slow (150 msec latency) | ||
| Conductance (nS) | 5 ± 1 | 6 ± 1 |
| Reversal potential (mV) | −83 ± 3 | −85 ± 4 |
-
Values represent mean ± SEM. There are no significant differences (t test).
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Dentate gyrus granule cell | resting membrane potential (mV) | -77.0 ± 2.0 (12) | -77.0 (mV) | Data Table | |
| Dentate gyrus granule cell | input resistance | 84.0 ± 8.0 (12) | 84.0 (MΩ) | Data Table | |
| Dentate gyrus granule cell | spike amplitude (mV) | 73.0 ± 2.0 (12) | 73.0 (mV) | Data Table |