Table 2
Summary of developmental changes in excitatory synaptic properties
| Age | P10-P14; n = 27 | P15-P18; n = 89 | P19-P29; n = 55 | F value | P value |
| Latency (ms) | 1.0 ± 0.3 | 1.1 ± 0.5 | 0.9 ± 0.3* | 5.3 | 0.034 |
| τr (ms) | 1.4 ± 0.6 | 1.4 ± 0.6 | 1.2 ± 0.7 | 2.5 | 0.082 |
| τd (ms) | 37 ± 26 | 20 ± 9** | 15 ± 8†† | 2.7 | 5 × 10-11 |
| tpeak (ms) | 6 ± 2 | 6 ± 2 | 5 ± 2 | 3.0 | 0.053 |
| Amplitude (mV) | 1.8 ± 1.6 | 1.3 ± 1.2 | 1.1 ± 0.9† | 3 | 0.047 |
| Fail rate | 0.10 ± 0.13 | 0.14 ± 0.14 | 0.14 ± 0.16† | n/a | n/a |
| PPR | 0.4 ± 0.1 | 0.7 ± 0.2** | 0.8 ± 0.2†† | 22 | 2.6 × 10-9 |
| Vm (mV) | -66 ± 6 | -73 ± 4** | -73 ± 4†† | 33 | 6.5 × 10-13 |
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Note: τr, EPSP rise constant; τd, EPSP decay constant; tpeak, time to peak from onset; n/a, not applicable; PPR, paired pulse ratio; Vm, membrane potential at which PSPs were recorded. Significance at **P < 0.01, *P < 0.05 with column to immediate left (i.e., P10-P14 vs. P15-P18 and P15-P18 vs. P19-P29), ††P < 0.01, †P < 0.05 for P10-P14 versus P19-P29. F values and P values are for ANOVA comparisons between multiple age groups. ANOVA was n/a for statistical analysis of synaptic failure rate.