Age | P10-P14; n = 26 | P15-P18; n = 97 | P19-P29; n = 65 | F value | P value |
Latency (ms) | 0.8 ± 0.4 | 0.9 ± 0.3 | 0.6 ± 0.3**†† | 11 | 2.0 × 10-5 |
τr (ms) | 6 ± 3 | 4 ± 1** | 3 ± 1**†† | 14 | 1.6 × 10-6 |
τd (ms) | 68 ± 34 | 54 ± 30 | 50 ± 31† | 3.4 | 0.04 |
tpeak (ms) | 16 ± 5 | 13 ± 3** | 13 ± 4†† | 12 | 1.3 × 10-5 |
Amplitude (mV) | 0.8 ± 0.5 | 0.7 ± 0.2 | 0.5 ± 0.3*†† | 6.9 | 1.0 × 10-3 |
Fail rate | 0.12 ± 0.12 | 0.11 ± 0.14 | 0.14 ± 0.14 | n/a | n/a |
PPR | 0.7 ± 0.2 | 0.7 ± 0.2 | 0.7 ± 0.2 | 2.7 | 0.07 |
Vm (mV) | -59 ± 5 | -61 ± 3 | -61 ± 3 | 0.93 | 0.4 |
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Note: τr, IPSP rise constant; τd, IPSP decay constant; tpeak, time to peak from onset; n/a, not applicable; PPR, paired pulse ratio; Vm, membrane potential at which PSPs were recorded. Significance at **P < 0.01, *P < 0.05 with column to immediate left (i.e., P10-P14 vs. P15-P18 and P15-P18 vs. P19-P29), ††P < 0.01, †P < 0.05 for P10-P14 versus P19-P29. F values and P values are for ANOVA comparisons between multiple age groups. ANOVA was n/a for statistical analysis of synaptic failure rate.