Table 2
LSPS-evoked and spontaneous EPSCs
| Layer 2/3 | Layer 5 | |||||
| Sham, n = 13 | FL, n = 13 | P | Sham, n = 12 | FL, n = 12 | P | |
| LSPS-evoked EPSCs | ||||||
| Cumulative amplitude/spot (pA) | ||||||
| From all layers | 3.04 ± 0.58 | 3.92 ± 0.65 | - | 4.53 ± 0.56 | 7.56 ± 0.77 | ** |
| From layer 2/3 | 2.47 ± 0.25 | 3.55 ± 0.70 | - | 4.23 ± 0.75 | 7.56 ± 1.53 | - |
| From layer 4/5a | 4.10 ± 1.10 | 5.51 ± 1.05 | - | 4.23 ± 0.67 | 4.60 ± 0.39 | - |
| From layer 5/6 | 2.54 ± 0.58 | 2.70 ± 0.66 | - | 5.46 ± 1.11 | 10.73 ± 2.26 | * |
| Amplitude/kinetics versus number of eventsa | ||||||
| Amplitude (pA) | 9.36 ± 0.68 | 9.33 ± 0.52 | - | 10.65 ± 0.88 | 9.90 ± 0.66 | - |
| 90% rise (ms) | 1.61 ± 0.04 | 1.61 ± 0.05 | - | 1.64 ± 0.07 | 1.52 ± 0.05 | - |
| Half width (ms) | 8.07 ± 0.52 | 7.75 ± 0.41 | - | 8.48 ± 0.62 | 7.11 ± 0.39 | - |
| # of EPSCs/spot | 0.621 ± 0.060 | 0.770 ± 0.020 | - | 0.546 ± 0.042 | 0.824 ± 0.034 | * |
| Spontaneous EPSCs | ||||||
| Amplitude (pA) | 7.46 ± 0.52 | 6.94 ± 0.20 | - | 7.62 ± 0.53 | 7.30 ± 0.40 | - |
| 90% rise (ms) | 1.52 ± 0.03 | 1.47 ± 0.03 | - | 1.52 ± 0.04 | 1.45 ± 0.05 | - |
| Half width (ms) | 8.23 ± 0.55 | 7.71 ± 0.47 | - | 8.42 ± 0.53 | 7.40 ± 0.39 | - |
| Frequency (Hz) | 10.48 ± 1.22 | 13.30 ± 1.15 | - | 8.42 ± 1.39 | 13.57 ± 2.05 | * |
-
Note: Origin and properties of spontaneous and LSPS-evoked EPSCs onto pyramidal cells in FL and sham-operated cortex.
-
↵a Refers to LSPS-evoked EPSCs from all layers. *P < 0.05; **P < 0.01; -, not significant, P > 0.05.