RMP (mV) | Rin (MΩ) | Firing Freqinitial.(Hz) | AP1 half-width (ms) | Accommodation index (t(AP2 - AP1)/t(APn-1 - APn)) | |
Petilla | |||||
NGFC (72) | -73.4 ± 0.5 | 107 ± 3 | 23.0 ± 1.6 | 0.48 ± 0.01 | 1.12 ± 0.04 |
FS (23) | -72.0 ± 1.1 | 87 ± 7 | 93.0 ± 12.5 | 0.28 ± 0.01 | 0.93 ± 0.1 |
c-AC (137) | 67.3 ± 0.4 | 166 ± 5 | 44.5 ± 4.2 | 0.5 ± 0.01 | 0.50 ± 0.02 |
BS (34) | -69.2 ± 0.9 | 201 ± 15 | 285.9 ± 11.3 | 0.43 ± 0.01 | 0.09 ± 0.01 |
Clustering | |||||
Cluster 1 (81) (81% NGFC) | -74.0 ± 0.4 (-74.1 ± 0.5) | 108 ± 3 (106 ± 3) | 23.8 ± 2.3 (21.7 ± 1.5) | 0.49 ± 0.1 (0.48 ± 0.01) | 1.06 ± 0.04 (1.14 ± 0.04) |
Cluster 2 (24) (96% FS) | -72.0 ± 1.1 (-72.0 ± 1.1) | 88 ± 7 (87 ± 8) | 92.8 ± 12.0 (93.0 ± 12.5) | 0.28 ± 0.01 (0.28 ± 0.01) | 0.91 ± 0.1 (0.93 ± 0.1) |
Cluster 3 (125) (94% c-AC) | -66.2 ± 0.4 (-66.4 ± 0.4) | 167 ± 4 (169 ± 4) | 41.2 ± 3.2 (39.7 ± 3.2) | 0.50 ± 0.01 (0.50 ± 0.01) | 0.51 ± 0.02 (0.49 ± 0.02) |
Cluster 4 (36) (89% BS) | -69.7 ± 0.7 (-69.8 ± 0.8) | 209 ± 17 (202 ± 16) | 286.3 ± 11.3 (295.2 ± 9.9) | 0.43 ± 0.01 (0.43 ± 0.01) | 0.09 ± 0.01 (0.08 ± 0.01) |
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Petilla: The active and passive properties of L1 neurons grouped according to the Petilla classification scheme (c-AC, NGFC, FS, and BS). Number of neurons are given in brackets. Clustering: unsupervised clustering (hierarchical clustering using Ward's method) was performed and a cut off criteria was determined to reveal 4 clusters. Number of neurons in each cluster are given in brackets. The primary composition of neurons in each cluster when identified by the Petilla classification scheme are indicated: 81% of neurons in cluster 1 were NGFCs, 96% of neurons in cluster 2 FS neurons, 94% of neurons in cluster 3 c-AC neurons, and 89% of neurons in cluster 4 BS neurons. The average values for the active and passive properties for the primary composition of neurons in each cluster. All values are given as mean ± standard error of the mean.