Table 2
Excitatory post-synaptic currents
| Layer | Basal frequency (Hz) | Frequency with 5-HT (Hz) | Basal amplitude (pA) | Amplitude with 5-HT (pA) |
|---|---|---|---|---|
| Baseline EPSC frequency and amplitude were recorded in voltage clamp mode with the holding potential near the resting Vm. The effect of 1 min of application of 100 μM serotonin was then determined (mean ± SEM). | ||||
| *Change from baseline: P ≤ 0.001. | ||||
| II/III | 4.1 ± 0.6 | 6.9 ± 1.3 | 43.6 ± 9.9 | 43.5 ± 9.2 |
| V | 4.5 ± 0.7 | 18.4 ± 2.3* | 47.8 ± 6.0 | 55.6 ± 7.5 |
| VI | 4.7 ± 0.5 | 6.2 ± 0.8 | 31.4 ± 6.3 | 30.3 ± 6.3 |