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Article: Quantitative chemical composition of cortical GABAergic neurons revealed in transgenic venus-expressing rats.

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Uematsu M; Hirai Y; Karube F; Ebihara S; Kato M; Abe K; Obata K; Yoshida S; Hirabayashi M; Yanagawa Y; Kawaguchi Y
Cereb. Cortex, 2008


Table 2

Colocalization of chemical markers for GABAergic nonpyramidal cells with Venus in frontal cortex of VGAT-Venus rats

Layer PV SOM VIP CCK αAc2
VGAT-Venus-A
    I No cells No cells 100% (6) 100% (4) 100% (104)
    II/III 99.8% (470) 98.6% (142) 98.3% (359) 100% (165) 100% (154)
    V 100% (378) 96.2% (132) 98.8% (85) 100% (28) 100% (15)
    VI 99.7% (306) 98.1% (211) 97.6% (85) 97.7% (43) 100% (52)
    Total 99.8% (1154) 97.7% (485) 98.3% (535) 99.6% (240) 100% (325)
VGAT-Venus-B
    I No cells No cells 28.6% (7) 0.0% (1) 47.0% (134)
    II/III 99.7% (622) 98.2% (336) 88.5% (226) 88.9% (235) 59.6% (136)
    V 99.9% (731) 98.8% (248) 95.0% (60) 82.9% (41) 85.7% (14)
    VI 99.7% (751) 98.4% (189) 95.1% (61) 94.8% (58) 74.5% (47)
    Total 99.8% (2104) 98.4% (773) 89.5% (354) 89.0% (335) 57.7% (331)
  • Note: Venus cells/cells positive for a chemical marker. Data are combined from 3 animals in A line, 2 animals in B line. ( ), number of cells positive for individual chemical markers (denominator). PV, parvalbumin; SOM, somatostatin; αAc2, α-actinin-2.


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