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Article: Functional roles of Kv1 channels in neocortical pyramidal neurons.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Guan D; Lee JC; Higgs MH; Spain WJ; Foehring RC
J. Neurophysiol., 2007



TABLE 2.Slice data: 3-s current injections


Rn Rheobase fI Slope

Control 202 ± 72 (n = 13) 160 ± 74 (n = 23) 0.088 ± 0.05 (n = 13)
DTX 215 ± 69 (n = 13) 108 ± 47 (n = 27)* 0.110 ± 0.04 (n = 13)*

Values are means ± SD; values of n (whole cell recordings) are in parentheses. Rn, input resistance = V/I (MΩ); Rheobase, lowest current to elicit an AP (pA); fI (frequency–current) slope, between 1 and 2 s firing (Hz/pA). Statistical significance:

* P < 0.05.


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 2-3 rheobase 160.0 ± 74.0 160.0 (pA) Data Table
Neocortex pyramidal cell layer 2-3 FI slope 0.088 ± 0.05 0.088 (Hz/nA) Data Table
Neocortex pyramidal cell layer 2-3 input resistance 202.0 ± 72.0 202.0 (MΩ) Data Table