TABLE 1.Passive and active membrane properties of NVsnpr neurons classified according to their firing patterns
|
|
||||
| Parameter | Adaptive | Tonic | Burst and Tonic | Repetitive Bursting |
|
|
||||
| N | 53 | 124 | 23 | 7 |
| (53) | (124) | (23) | (7) | |
| Vm, mV | –57 ± 1 | –56 ± 0.4 | –54 ± 1 | –58 ± 1 |
| Rm, MΩ | 521 ± 32‡vsT: †vsBT, RB | 347 ± 17 | 360 ± 32 | 219 ± 57 |
| τ, ms | 53.6 ± 2.5‡vsT: BT, RB | 36.6 ± 1.7 | 27.8 ± 3.1 | 18.1 ± 4.8 |
| (49) | (121) | (16) | (7) | |
| AP amp, mV | 63 ± 2 | 62 ± 1 | 62 ± 3 | 67 ± 8 |
| AP dur, ms | 2.9 ± 0.2‡vsT, BT, vsRB | 1.6 ± 0.1 | 1.2 ± 0.1 | 1.5 ± 0.2 |
| AP threshold, mV | –37 ± 1 | –39 ± 1 | –43 ± 1‡vsA, T | –48 ± 2‡vsA, T |
| Rheobase, nA | 0.042 ± 0.008 | 0.072 ± 0.009 | 0.021 ± 0.005 | 0.015 ± 0.004 |
| ADP, % | 34.9 | 47.5 | 100 | 100 |
| (28) | (100) | (12) | (5) | |
| AHP amp, mV | –5.9 ± 0.6 | –7.5 ± 0.3 | –6.5 ± 0.9 | –5.4 ± 1.3 |
| AHP dur, ms | 167 ± 9‡vsT, BT | 103 ± 4 | 82 ± 10 | 119 ± 25 |
†P < 0.01,
‡ P < 0.001 (I-way ANOVA). N = number of cells. Number of observations are in parentheses. NVsnpr, trigeminal principal sensory nucleus; A, adaptive; T, tonic; BT, burst and tonic; RB, repetitive bursting; ADP, afterdepolarization, AHP, afterhyperpolarization, AP, action potential.