Article: Nicotinic receptor subtype-selective circuit patterns in the subthalamic nucleus.
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Xiao C; Miwa JM; Henderson BJ; Wang Y; Deshpande P; McKinney SL; Lester HA
J. Neurosci., 2015
Table 2.
Chronic nicotine effects on ACh currents in STN neurons
| Treatment |
n |
Vehicle |
n |
Nicotine |
p |
| 7 d |
|
|
|
|
|
| α4β2 |
13 |
49 ± 10 |
15 |
63 ± 13 |
0.38 |
| α7 |
18 |
87 ± 15 |
20 |
89 ± 22 |
0.95 |
| 14 d |
|
|
|
|
|
| α4β2 |
22 |
46 ± 7 |
23 |
73 ± 7 |
0.009 |
| α7 |
19 |
94 ± 19 |
21 |
82 ± 15 |
0.37 |
| 3 weeks withdrawal |
|
|
|
|
|
| α4β2 |
11 |
35 ± 6 |
15 |
43 ± 11 |
0.55 |
| α7 |
11 |
93 ± 19 |
9 |
88 ± 22 |
0.86 |
Inferred neuron-electrophysiology data values
| Neuron Type |
Neuron Description |
Ephys Prop |
Extracted Value |
Standardized Value |
Content Source |
