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Article: Altered calcium metabolism in aging CA1 hippocampal pyramidal neurons.

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Oh MM; Oliveira FA; Waters J; Disterhoft JF
J. Neurosci., 2013


Table 1.

Membrane properties of CA1 pyramidal neurons

Young 27 neurons Aging 22 neurons
Resting membrane potential (mV) -66.6 ± 0.7 -66.3 ± 1.1
Input resistance (MΩ) 67.6 ± 3.0 56.2 ± 3.0
AP threshold (mV) -49.6 ± 1.3 -52.1 ± 1.1
AP amplitude (mV) 83.1 ± 2.2 86.7 ± 1.8
AP half width (ms) 0.85 ± 0.03 0.78 ± 0.03
  • A summary of membrane properties of CA1 pyramidal neurons in young and aging rats. All values are mean ± SEM


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell spike amplitude (mV) 83.1 ± 2.2 (27) 83.1 (mV) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 86.7 ± 1.8 (22) 86.7 (mV) Data Table
Hippocampus CA1 pyramidal cell spike half-width (ms) 0.85 ± 0.03 (27) 0.85 (ms) Data Table
Hippocampus CA1 pyramidal cell spike half-width (ms) 0.78 ± 0.03 (22) 0.78 (ms) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -66.6 ± 0.7 (27) -66.6 (mV) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -66.3 ± 1.1 (22) -66.3 (mV) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 67.6 ± 3.0 (27) 67.6 (MΩ) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 56.2 ± 3.0 (22) 56.2 (MΩ) Data Table
Hippocampus CA1 pyramidal cell spike threshold (mV) -49.6 ± 1.3 (27) -49.6 (mV) Data Table
Hippocampus CA1 pyramidal cell spike threshold (mV) -52.1 ± 1.1 (22) -52.1 (mV) Data Table