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Article: Brain activity mapping in Mecp2 mutant mice reveals functional deficits in forebrain circuits, including key nodes in the default mode network, that are reversed with ketamine treatment.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Kron M; Howell CJ; Adams IT; Ransbottom M; Christian D; Ogier M; Katz DM
J. Neurosci., 2012


Table 4.

Action potential properties of second-order nComm nTS relay neurons

AP properties Wt (n = 15) Null (n = 16)
Threshold (mV) -31.68 ± 1.56 -34.24 ± 1.34
Rise time (ms) 0.91 ± 0.04 0.82 ± 0.05
Amplitude (mV) 76.05 ± 2.38 74.24 ± 2.76
Decay time (ms) 0.70 ± 0.02 0.64 ± 0.03
AHP (mV) -24.33 ± 1.60 -21.94 ± 1.26

  • Data are displayed as mean ± SEM; *p < 0.05; AP, Action potential; AHP, fast afterhyperpolarization.


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Nucleus of the solitary tract principal cell nucleus tractus solitarius second-order commissural Fos-positive relay neuron spike amplitude (mV) 76.05 ± 2.38 (15) 76.05 (mV) Data Table
Nucleus of the solitary tract principal cell nucleus tractus solitarius second-order commissural Fos-positive relay neuron spike decay time (ms) 0.7 ± 0.02 (15) 0.7 (ms) Data Table
Nucleus of the solitary tract principal cell nucleus tractus solitarius second-order commissural Fos-positive relay neuron AHP amplitude (mV) -24.33 ± 1.6 (15) 24.33 (mV) Data Table
Nucleus of the solitary tract principal cell nucleus tractus solitarius second-order commissural Fos-positive relay neuron spike threshold (mV) -31.68 ± 1.56 (15) -31.68 (mV) Data Table
Nucleus of the solitary tract principal cell nucleus tractus solitarius second-order commissural Fos-positive relay neuron spike rise time (ms) 0.91 ± 0.04 (15) 0.91 (ms) Data Table