Article: COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Lacroix A; Toussay X; Anenberg E; Lecrux C; Ferreirós N; Karagiannis A; Plaisier F; Chausson P; Jarlier F; Burgess SA; Hillman EM; Tegeder I; Murphy TH; Hamel E; Cauli B
J. Neurosci., 2015

Table 1.

Morphological and physiological properties of diving arterioles

	Ctrl (n = 16)	Indo (n = 6)	SC 560 (n = 12)	NS 398 (n = 10)	AH 6809 (n = 14)	L 161-982 (n = 11)	CAY 10441 (n = 12)	TTX (n = 8)
Resting luminal diameter, μm	17.3 ± 1.9	14.0 ± 2.5	19.3 ± 2.2	16.1 ± 1.2	14.9 ± 1.4	16.9 ± 2.4	16.6 ± 1.5	16.3 ± 2.2
		U_(16,6) = 36	U_(16,12) = 78	U_(16,10) = 80	U_(16,14) = 95	U_(16,11) = 79	U_(16,12) = 93	U_(16,8) = 61
		p = 0.407007	p = 0.42275	p = 1	p = 0.49841	p = 0.680026	p = 0.909139	p = 0.880976
					n.s.
Wall thickness, μm	4.9 ± 0.4	4.6 ± 0.5	4.2 ± 0.4	4.7 ± 0.4	4.9 ± 0.4	5.2 ± 0.5	4.2 ± 0.4	3.9 ± 0.6
		U_(16,6) = 40	U_(16,12) = 79	U_(16,10) = 75.5	U_(16,14) = 110	U_(16,11) = 76	U_(16,12) = 83	U_(16,8) = 37
		p = 0.590031	p = 0.449918	p = 0.815935	p = 0.951039	p = 0.576537	p = 0.567585	p = 0.105638
					n.s.
Resting stability, %	1.2 ± 0.2	1.6 ± 0.2	1.4 ± 0.2	1.5 ± 0.2	1.4 ± 0.2	1.7 ± 0.3	1.4 ± 0.1	1.3 ± 0.2
		U_(16,6) = 25	U_(16,12) = 73	U_(16,10) = 57.5	U_(16,14) = 93	U_(16,11) = 61	U_(16,12) = 72	U_(16,8) = 49
		p = 0.098026	p = 0.301529	p = 0.240562	p = 0.447547	p = 0.194506	p = 0.28029	p = 0.382604
					n.s.
Constriction level, %	46.5 ± 3.2	46.0 ± 6.5	45.1 ± 4.9	39.4 ± 5.0	37.5 ± 3.5	37.2 ± 4.5	37.2 ± 3.5	35.3 ± 4.8
		U_(16,6) = 45	U_(16,12) = 93.5	U_(16,10) = 52	U_(16,14) = 69	U_(16,11) = 58.5	U_(16,12) = 57	U_(16,8) = 37.5
		p = 0.857733	p = 0.909139	p = 0.149647	p = 0.077067	p = 0.14767	p = 0.07354	p = 0.105638
					n.s.
Constriction stability, %	3.4 ± 0.6	3.9 ± 0.7	3.2 ± 0.6	3.1 ± 0.4	3.1 ± 0.5	3.1 ± 0.6	2.6 ± 0.4	2.4 ± 0.2
		U_(16,6) = 35	U_(16,12) = 92.5	U_(16,10) = 74	U_(16,14) = 105	U_(16,11) = 85	U_(16,12) = 82	U_(16,8) = 50
		p = 0.366773	p = 0.873052	p = 0.775995	p = 0.790107	p = 0.903538	p = 0.536889	p = 0.41665
					n.s.

Ctrl, Control; Indo, indomethacin; SC 560, COX-1 inhibitor; NS 398, COX-2 inhibitor; AH 6809, EP1/2 receptor antagonist; L 161-982, EP4 receptor antagonist; CAY 10441, IP receptor antagonist; TTX, tetrodotoxin; n, number of diving arterioles. Values are mean ± SEM Mann-Whitney U test and corresponding exact p values. n.s., not statistically significant from control condition with Bonferroni correction for multiple comparisons.

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Inferred neuron-electrophysiology data values

Neuron Type	Neuron Description	Ephys Prop	Extracted Value	Standardized Value	Content Source