Article: COX-2-Derived Prostaglandin E2 Produced by Pyramidal Neurons Contributes to Neurovascular Coupling in the Rodent Cerebral Cortex.
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Lacroix A; Toussay X; Anenberg E; Lecrux C; Ferreirós N; Karagiannis A; Plaisier F; Chausson P; Jarlier F; Burgess SA; Hillman EM; Tegeder I; Murphy TH; Hamel E; Cauli B
J. Neurosci., 2015
Table 4.
In vivo neurovascular coupling response impairment by receptor antagonists
| Antagonist |
Concentration |
Effect on the peak CBF whisker response |
n |
| AH 6809 |
10-7 m |
-5.7 ± 4.5% |
4 |
| 10-6 m |
-28.2 ± 2.6% |
5 |
| 10-5 m |
-15.0 ± 3.8% |
6 |
| 10-4 m |
-6.1 ± 3.8% |
5 |
| L 161-982 |
10-4 m |
-17.7 ± 4.8% |
4 |
| CAY 10441 |
10-6 m |
+10.2 ± 11.8% |
3 |
| 10-5 m |
+10.4 ± 22.1% |
3 |
| 10-4 m |
+0.6 ± 8.7% |
5 |
Inferred neuron-electrophysiology data values
| Neuron Type |
Neuron Description |
Ephys Prop |
Extracted Value |
Standardized Value |
Content Source |
