AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Reversal of Aging-Related Neuronal Ca2+ Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Gant JC; Chen KC; Kadish I; Blalock EM; Thibault O; Porter NM; Landfield PW
J. Neurosci., 2015


Table 1.

Baseline electrophysiological measures for neurons from behaviorally characterized rats (means ± SEM)

Aged-FKBP1b Aged-Control Young F value p value
N animals 7 6 5
n neurons 17 16 13
Resting potential (mV) -59.88 ± 0.74 -59.44 ± 0.75 -59.39 ± 0.70 0.14 0.87
Input resistance (MΩ) 56.29 ± 2.02 53.81 ± 2.65 53.85 ± 3.92 0.27 0.76
AP height (mV) 83.91 ± 1.34 86.28 ± 1.47 87.94 ± 2.24 1.50 0.24

Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -59.44 ± 0.75 (16) -59.44 (mV) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -59.39 ± 0.7 (13) -59.39 (mV) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 53.81 ± 2.65 (16) 53.81 (MΩ) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 53.85 ± 3.92 (13) 53.85 (MΩ) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 86.28 ± 1.47 (16) 86.28 (mV) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 87.94 ± 2.24 (13) 87.94 (mV) Data Table