AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Selective suppression of excitatory synapses on GABAergic interneurons by norepinephrine in juvenile rat prefrontal cortical microcircuitry.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Wang HX; Waterhouse BD; Gao WJ
Neuroscience, 2013


P-FS (n = 7)
FS-P (n = 7)
P-P (n = 12)
Pre-NEPost-NEP ValuePre-NEPost-NEP ValuePre-NEPost-NEP Value
Presynaptic neuron
Resting membrane potential (mV)-67.9 ± 2.04-66.0 ± 2.100.131-70.0 ± 1.74-66.0 ± 1.800.222-65.7 ± 5.10-66.1 ± 6.920.878
Input resistance (MΩ)112 ± 16.3118 ± 22.30.572200 ± 31.6211 ± 38.80.50135 ± 48.9137 ± 38.80.820
Membrane time constant (ms)29.5 ± 3.1528.0 ± 3.260.6407.55 ± 1.368.70 ± 1.990.22126.5 ± 1.3325.0 ± 1.550.303
AP threshold (mV)-44.2 ± 1.88-3.7 ± 1.320.811-5.2 ± 1.12-3.4 ± 1.330.255-2.6 ± 1.23-1.2 ± 0.850.374
AP half-width (ms)1.79 ± 0.172.04 ± 0.210.1220.46 ± 0.120.47 ± 0.120.1362.24 ± 0.252.35 ± 0.230.697

Postsynaptic neuron
Inject current (pA)-17.5 ± 16.2-35.4 ± 14.60.14720.6 ± 14.9-2.8 ± 15.60.084-6.17 ± 12.1-2.99 ± 11.40.605
Latency (ms)0.52 ± 0.100.58 ± 0.060.3310.50 ± 0.060.48 ± 0.060.2780.99 ± 0.100.99 ± 0.090.918
Amplitude (pA)36.9 ± 15.610.4 ± 4.760.05830.5 ± 15.525.0 ± 13.40.14011.5 ± 2.0611.0 ± 3.020.861
20-80% Rise time (ms)0.71 ± 0.090.93 ± 0.190.2720.68 ± 0.070.96 ± 0.160.1231.41 ± 0.291.32 ± 0.170.577
63% Decay time (ms)5.50 ± 0.945.90 ± 1.190.71968.23 ± 0.8510.2 ± 1.550.096711.2 ± 1.799.50 ± 1.550.2649
Half-duration (ms)5.81 ± 1.105.88 ± 0.870.930412.7 ± 1.1812.8 ± 1.330.941110.8 ± 1.8010.7 ± 1.720.8806

Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to fast-spiking GABAergic interneurons input resistance (MΩ) 112.0 ± 16.3 (7) 112.0 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex inhibitory fast-spiking GABAergic interneurons projecting to layer 5 excitatory pyramidal neurons input resistance (MΩ) 200.0 ± 31.6 (7) 200.0 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to layer 5 excitatory pyramidal neurons input resistance (MΩ) 135.0 ± 48.9 (12) 135.0 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to fast-spiking GABAergic interneurons membrane time constant (ms) 29.5 ± 3.15 (7) 29.5 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex inhibitory fast-spiking GABAergic interneurons projecting to layer 5 excitatory pyramidal neurons membrane time constant (ms) 7.55 ± 1.36 (7) 7.55 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to layer 5 excitatory pyramidal neurons membrane time constant (ms) 26.5 ± 1.33 (12) 26.5 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to fast-spiking GABAergic interneurons resting membrane potential (mV) -67.9 ± 2.04 (7) -67.9 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to fast-spiking GABAergic interneurons spike threshold (mV) -44.2 ± 1.88 (7) -44.2 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex inhibitory fast-spiking GABAergic interneurons projecting to layer 5 excitatory pyramidal neurons spike threshold (mV) -5.2 ± 1.12 (7) -5.2 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to layer 5 excitatory pyramidal neurons spike threshold (mV) -2.6 ± 1.23 (12) -- Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to fast-spiking GABAergic interneurons spike half-width (ms) 1.79 ± 0.17 (7) 1.79 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex inhibitory fast-spiking GABAergic interneurons projecting to layer 5 excitatory pyramidal neurons spike half-width (ms) 0.46 ± 0.12 (7) 0.46 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to layer 5 excitatory pyramidal neurons spike half-width (ms) 2.24 ± 0.25 (12) 2.24 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex inhibitory fast-spiking GABAergic interneurons projecting to layer 5 excitatory pyramidal neurons resting membrane potential (mV) -70.0 ± 1.74 (7) -70.0 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 excitatory pyramidal neurons projecting to layer 5 excitatory pyramidal neurons resting membrane potential (mV) -65.7 ± 5.1 (12) -65.7 (mV) Data Table