Article: A seizure-induced gain-of-function in BK channels is associated with elevated firing activity in neocortical pyramidal neurons.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Shruti S; Clem RL; Barth AL Neurobiol. Dis., 2008
Control | 24 h post-seizure | p value | |
---|---|---|---|
Resting potential (mV) | - 71.18 ± 3.51 (n = 20) | - 69.29 ± 0.68 (n = 26) | 0.07470 |
Input resistance (MΩ) | 378.84 ± 79.87 (n = 20) | 395.40 ± 20.19 (n = 26) | 0.55536 |
Rheobase (pA) | 117.10 ± 41.28 (n = 19) | 108.58 ± 6.17 (n = 26) | 0.43562 |
AP threshold (mV) | - 27.59 ± 0.86 (n = 17) | - 28.62 ± 0.70 (n = 25) | 0.35815 |
AP waveform: | |||
Height (mV) | 74.71 ± 1.00 (n = 26) | 76.89 ± 1.10 (n = 25) | 0.14875 |
Half-width (ms) | 2.93 ± 0.07 (n = 26) | 2.44 ± 0.06 (n = 25) | 0.00003 |
Rise time (ms) | 1.52 ± 0.04 (n = 26) | 1.50 ± 0.03 (n = 25) | 0.69828 |
Decay time (ms) | 3.00 ± 0.10 (n = 26) | 2.46 ± 0.06 (n = 25) | 0.00002 |
Area (mV * ms) | 204.22 ± 4.97 (n = 26) | 177.42 ± 2.81 (n = 25) | < 0.00001 |