Article: Optogenetic inhibition of chemically induced hypersynchronized bursting in mice.
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Berglind F; Ledri M; Sørensen AT; Nikitidou L; Melis M; Bielefeld P; Kirik D; Deisseroth K; Andersson M; Kokaia M
Neurobiol. Dis., 2014
Individual burst durations (ms)
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Naive | (n = 5) | | KA | (n = 6) | | Control | (n = 6) | |
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Pre | Light | | Pre | Light | | Pre | Light | |
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70 (29) | 54 (33) | | 83 (26) | 58 (27) | | 88 (29) | 87 (28) | |
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Total time of bursting per minute (s) |
Naive | (n = 5) | | KA | (n = 6) | | Control | (n = 6) | |
Pre | Light | Post | Pre | Light | Post | Pre | Light | Post |
2.1 (0.9) | 0.4 (0.3) | 2.6 (1.1) | 1.8 (0.5) | 0.3 (0.2) | 1.9 (0.7) | 1.7 (0.8) | 1.7 (0.7) | 1.7 (0.8) |
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Duration of first burst after light (ms) |
Naive | (n = 9) | | KA | (n = 8) | | Control | (n = 6) | |
Pre | First post | Pre | First post | Pre | First post |
70 (25) | 214 (216) | 74 (17) | 130 (72) | 88 (29) | 90 (27) |
Inferred neuron-electrophysiology data values
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