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Article: Strychnine-sensitive glycine receptors on pyramidal neurons in layers II/III of the mouse prefrontal cortex are tonically activated.

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Salling MC; Harrison NL
J. Neurophysiol., 2014


Table 2.

Characteristics of synaptic events (sIPSCs and mIPSCs) summarized for neurons before and after application of 1 μM strychnine

Events (cells)Freq, HzAmp, pARise, msDecay, ms
sIPSC
    ACSF1,239 (6)6.8 ± 239.4 ± 22.6 ± 0.18.6 ± 0.6
    STRY1,175 (6)6.7 ± 238.8 ± 32.7 ± 0.17.8 ± 0.6
mIPSC
    ACSF578 (5)2.4 ± 0.833 ± 42.2 ± 0.25.3 ± 0.4
    STRY439 (5)1.8 ± 0.729 ± 32.2 ± 0.24.3 ± 0.3
  • Values are mean ± SE characteristics of synaptic events [spontaneous (sIPSC) and miniature (mIPSC) inhibitory postsynaptic currents] summarized for neurons before (ACSF) and after application of 1 μM strychnine (STRY). Significant changes in mIPSC decay time (P < 0.05) are in boldface.


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source