AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Reduced excitatory drive in interneurons in an animal model of cortical dysplasia.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Xiang H; Chen HX; Yu XX; King MA; Roper SN
J. Neurophysiol., 2006



TABLE 1.Intrinsic membrane properties of interneurons and pyramidal cells


Type I

Type II

Pyramidal Cells

CD (16) Control (15) CD (30) Control (23) CD (11) Control (15)

Cm, pF 40 ± 2 41 ± 5 39 ± 3 41 ± 2 141 ± 5 145 ± 4
RMP, mV –60 ± 3 –61 ± 4 –57 ± 3 –59 ± 2 –66 ± 5 –68 ± 2
Rin, MΩ 190 ± 16 198 ± 17 166 ± 11 171 ± 14 75 ± 4 76 ± 7
AP
    FR, Hz 97 ± 6 164 ± 5 –17 ± 2 50 ± 3 20 ± 2 17 ± 3
    Amplitude, mV 65 ± 4 67 ± 6 73 ± 4 75 ± 6 93 ± 6 95 ± 4
    Half width, ms 0.91 ± 0.2 0.86 ± 0.2 1.5 ± 0.1 1.4 ± 0.1 1.6 ± 0.2 1.5 ± 0.1

Values are means ± SE. The numbers of tested neurons are in parentheses. Cm membrane capacitance; RMP. resting member potential: Rin input resistance; AP, action potential; FR, firing rate.

Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex basket cell Somatosensory cortex layer 4-5 multipolar fast-spiking parvalbumin positive GABAergic interneuron cell capacitance (pF) 41.0 ± 5.0 (15) 41.0 (pF) Data Table
Neocortex Martinotti cell Somatosensory cortex layer 4-5 bipolar somatostatin immunopositive GABAergic interneuron cell capacitance (pF) 41.0 ± 2.0 (23) 41.0 (pF) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer 5 pyramidal cell cell capacitance (pF) 145.0 ± 4.0 (15) 145.0 (pF) Data Table
Neocortex basket cell Somatosensory cortex layer 4-5 multipolar fast-spiking parvalbumin positive GABAergic interneuron resting membrane potential (mV) -61.0 ± 4.0 (15) -61.0 (mV) Data Table
Neocortex Martinotti cell Somatosensory cortex layer 4-5 bipolar somatostatin immunopositive GABAergic interneuron resting membrane potential (mV) -59.0 ± 2.0 (23) -59.0 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer 5 pyramidal cell resting membrane potential (mV) -68.0 ± 2.0 (15) -68.0 (mV) Data Table
Neocortex basket cell Somatosensory cortex layer 4-5 multipolar fast-spiking parvalbumin positive GABAergic interneuron input resistance (MΩ) 198.0 ± 17.0 (15) 198.0 (MΩ) Data Table
Neocortex Martinotti cell Somatosensory cortex layer 4-5 bipolar somatostatin immunopositive GABAergic interneuron input resistance (MΩ) 171.0 ± 14.0 (23) 171.0 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer 5 pyramidal cell input resistance (MΩ) 76.0 ± 7.0 (15) 76.0 (MΩ) Data Table
Neocortex basket cell Somatosensory cortex layer 4-5 multipolar fast-spiking parvalbumin positive GABAergic interneuron firing frequency (Hz) 164.0 ± 5.0 (15) 164.0 (Hz) Data Table
Neocortex Martinotti cell Somatosensory cortex layer 4-5 bipolar somatostatin immunopositive GABAergic interneuron firing frequency (Hz) 50.0 ± 3.0 (23) 50.0 (Hz) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer 5 pyramidal cell firing frequency (Hz) 17.0 ± 3.0 (15) 17.0 (Hz) Data Table
Neocortex basket cell Somatosensory cortex layer 4-5 multipolar fast-spiking parvalbumin positive GABAergic interneuron spike amplitude (mV) 67.0 ± 6.0 (15) 67.0 (mV) Data Table
Neocortex Martinotti cell Somatosensory cortex layer 4-5 bipolar somatostatin immunopositive GABAergic interneuron spike amplitude (mV) 75.0 ± 6.0 (23) 75.0 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer 5 pyramidal cell spike amplitude (mV) 95.0 ± 4.0 (15) 95.0 (mV) Data Table
Neocortex basket cell Somatosensory cortex layer 4-5 multipolar fast-spiking parvalbumin positive GABAergic interneuron spike half-width (ms) 0.86 ± 0.2 (15) 0.86 (ms) Data Table
Neocortex Martinotti cell Somatosensory cortex layer 4-5 bipolar somatostatin immunopositive GABAergic interneuron spike half-width (ms) 1.4 ± 0.1 (23) 1.4 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Somatosensory cortex layer 5 pyramidal cell spike half-width (ms) 1.5 ± 0.1 (15) 1.5 (ms) Data Table