Article: Anti-GAD65 Containing Cerebrospinal Fluid Does not Alter GABAergic Transmission.
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Hackert JK; Müller L; Rohde M; Bien CG; Köhling R; Kirschstein T
Front Cell Neurosci, 2016
Kinetic properties of GABAA-receptor mediated IPSCs (patch-clamp recordings).
Kinetic property |
Control (n = 7) |
Anti-GAD (n = 7) |
P value |
Rise time constant (τrise) |
3.6 ± 0.6 ms |
4.0 ± 0.7 ms |
0.76 |
Decay time constant (τdecay) |
69.0 ± 7.3 ms |
69.9 ± 1.2 ms |
0.96 |
IPSC width at 10% |
185.8 ± 17.5 ms |
185.4 ± 26.2 ms |
0.99 |
Latency |
3.3 ± 0.3 ms |
3.2 ± 0.3 ms |
0.80 |
Charge (AUC) |
-42.6 ± 10.4 pC |
-87.1 ± 28.9 pC |
0.20 |
Coefficient of variation |
4.7 ± 0.9 % |
4.1 ± 0.8 % |
0.51 |
Inferred neuron-electrophysiology data values
Neuron Type |
Neuron Description |
Ephys Prop |
Extracted Value |
Standardized Value |
Content Source |