Article: Dynorphin-Dependent Reduction of Excitability and Attenuation of Inhibitory Afferents of NPS Neurons in the Pericoerulear Region of Mice.

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Jüngling K; Blaesse P; Goedecke L; Pape HC
Front Cell Neurosci, 2016

Table 1

Summary of passive and active membrane properties recorded in the current-clamp mode at a membrane potential of -60 mV during baseline and in presence of DynA (n = 14).

	Baseline		DynA
	Mean	SEM	Mean	SEM	p-value
R_in [MΩ]	629	51	431	43	0.01
Tau [ms]	38.2	1.9	32.7	3.3	0.17
Threshold [mV]	-41.2	0.6	-38.9	1.0	0.06
AP amplitude [mV]	73.7	0.7	68.4	0.9	0.03
AHP [mV]	17.6	0.6	18.8	0.5	0.15
Half-width [ms]	1.2	0.1	1.1	0.1	0.31
slAHP [mV]	3.1	0.5	1.4	0.3	0.01
Amplitude_last [mV]	53.7	2.2	53.3	2.8	0.92
AHPlast [mV]	17.0	0.9	18.8	0.7	0.13
Inst. frequency [Hz]	34.8	1.7	28.7	2.5	0.06
Time to 1st AP [ms]	12.2	0.8	14.0	1.3	0.25

Significant changes are marked in bold. Differences with a strong trend, but not reaching the p < 0.05 significance criteria are marked in italic.

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Inferred neuron-electrophysiology data values

Neuron Type	Neuron Description	Ephys Prop	Extracted Value	Standardized Value	Content Source
Other	pericoerulear locus neuropeptide S-expressing neuron	spike threshold	-41.2 (14)	-41.2 (mV)	Data Table
Other	pericoerulear locus neuropeptide S-expressing neuron	input resistance	629.0 (14)	629.0 (MΩ)	Data Table
Other	pericoerulear locus neuropeptide S-expressing neuron	spike amplitude	73.7 (14)	73.7 (mV)	Data Table
Other	pericoerulear locus neuropeptide S-expressing neuron	AHP amplitude	17.6 (14)	17.6 (mV)	Data Table
Other	pericoerulear locus neuropeptide S-expressing neuron	spike half-width	1.2 (14)	1.2 (ms)	Data Table
Other	pericoerulear locus neuropeptide S-expressing neuron	slow AHP amplitude	3.1 (14)	3.1 (mV)	Data Table
Other	pericoerulear locus neuropeptide S-expressing neuron	firing frequency	34.8 (14)	34.8 (Hz)	Data Table
Other	pericoerulear locus neuropeptide S-expressing neuron	first spike latency (1st)	12.2 (14)	--	Data Table
Other	pericoerulear locus neuropeptide S-expressing neuron	membrane time constant (Tau)	38.2 (14)	--	Data Table