AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Local-Circuit Phenotypes of Layer 5 Neurons in Motor-Frontal Cortex of YFP-H Mice.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Yu J; Anderson CT; Kiritani T; Sheets PL; Wokosin DL; Wood L; Shepherd GM
Front Neural Circuits, 2008


Table 1: Electrophysiological properties of YFP-positive and negative neurons in primary motor cortex curated from article text and figure 5
resting Vm (mV) input resistance (Mohm) capacitance (pF) ISI ratio (1st / last) Adaptation index
YFP+ −62 ± 5 153 ± 90 127 ± 80 0.49 1.071239
YFP− −62 ± 4 145 ± 63 139 ± 64 0.33 0.713871
: We did not find significant differences between YPF-positive (n = 24) and YFP-negative (n = 19) neurons in basic electrophysiological parameters, including resting membrane potential (YFP+, −62 ± 5 mV; YFP−, −62 ± 4 mV; mean ± s.d.; p > 0.05, t-test), input resistance (YFP+, 153 ± 90 MΩ; YFP−, 145 ± 63 MΩ; mean ± s.d.; p > 0.05, t-test), or capacitance (YFP+, 127 ± 80 mV; YFP−, 139 ± 64 mV; mean ± s.d.; p > 0.05, t-test). Comparison of spike frequency adaptation in YFP-positive and YFP-negative neurons. (A) Spike latencies were used to calculate instantaneous firing rates for the neurons in each group, and these were binned in 100-ms bins for averaging. The plot shows the mean (±s.e.m.) instantaneous firing rate as a function of time after step onset. Inset shows representative examples of spike patterns of YFP-positive (gray trace) and YFP-negative (black trace) neurons evoked by depolarizing current steps. Scale bars, 0.2 s, 50 mV. (B) Average adaptation index for YFP-negative (open) and YFP-positive (gray) neurons. The group averages were significantly different (*, p 

Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 5-6 primary motor cortex layer 5 thick tufted pyramidal cell cell capacitance (pF) 139.0 ± 64.0 (19) 139.0 (pF) Data Table
Neocortex pyramidal cell layer 5-6 primary motor cortex layer 5 thick tufted pyramidal cell adaptation ratio 0.33 (19) 0.33 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 primary motor cortex layer 5 thick tufted pyramidal cell adaptation ratio 0.713871 (19) 0.713871 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 primary motor cortex layer 5 Thy1-expressing thick tufted pyramidal cell resting membrane potential (mV) -62.0 ± 5.0 (24) -62.0 (mV) Data Table
Neocortex pyramidal cell layer 5-6 primary motor cortex layer 5 Thy1-expressing thick tufted pyramidal cell input resistance (Mohm) 153.0 ± 90.0 (24) 153.0 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 primary motor cortex layer 5 Thy1-expressing thick tufted pyramidal cell cell capacitance (pF) 127.0 ± 80.0 (24) 127.0 (pF) Data Table
Neocortex pyramidal cell layer 5-6 primary motor cortex layer 5 Thy1-expressing thick tufted pyramidal cell adaptation ratio 0.49 (24) 0.49 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 primary motor cortex layer 5 Thy1-expressing thick tufted pyramidal cell adaptation ratio 1.071239 (24) 1.071239 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 primary motor cortex layer 5 thick tufted pyramidal cell resting membrane potential (mV) -62.0 ± 4.0 (19) -62.0 (mV) Data Table
Neocortex pyramidal cell layer 5-6 primary motor cortex layer 5 thick tufted pyramidal cell input resistance (Mohm) 145.0 ± 63.0 (19) 145.0 (MΩ) Data Table