CGRP-ir Neurons | %Total TG Neurons |
---|---|
Small IB4− | 51 |
CGRP+ | 42* |
CGRP− | 9 |
Small IB4+ | 29 |
CGRP+ | 9 |
CGRP− | 20 |
Medium sized | 20 |
CGRP+ | 7 |
CGRP− | 13 |
-
For all groups, n = 450 neurons. TG, trigeminal ganglion.
-
↵* The majority (82%) of the small isolectin B4− (IB4−) neurons contain calcitonin gene-related peptide-immunoreactivity (CGRP-ir) and thus are peptidergic nociceptors. On the other hand, most (72%) of the CGRP+ neurons belong to the small IB4− TG subpopulation.