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Article: Interneurons in area CA1 stratum radiatum and stratum oriens remain functionally connected to excitatory synaptic input in chronically epileptic animals.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Rempe DA; Bertram EH; Williamson JM; Lothman EW
J. Neurophysiol., 1997


Table 2.

Intrinsic membrane properties of CA1 area neurons

Neuron Type Group RMP, mV AP Overshoot, mV AP Threshold, mV Membrane Impedance, MΩ AP Half-Height Weidth, ms Spontaneous APs
Stratum radiatm-L/M interneurons Control (35) −60 ± 0.9 20 ± 1.4* −45 ± 0.7 279  ± 15 1.2 ± 0.1 18%
post-SSLSE (27) −59 ± 1 24 ± 1* −46 ± 0.6 274  ± 19 1.2 ± 0.04 38%
Stratum oriens interneurons Control (19) −57 ± 1 24 ± 2 −47 ± 0.8 272  ± 25 1.1 ± 0.1 61%
post-SSLSE (12) −59 ± 2 25 ± 3 −48 ± 1 394  ± 71 1.2 ± 0.1 50%
Pyramidal cells All (32) −63 ± 1** 42 ± 2** Not Measured 70.6 ± 4** 1.3 ± 0.04 0%

  • Parentheses contain number of neurons. Values are means ± SE. The last column is the percentage of cells with spontaneous APs at their RMP. RMP, resting membrane potential; AP, action potential.

  • ↵* P < 0.05 (t-test) comparing interneurons (same location) in control versus post-SSLSE tissue;** P < 0.001 (t-tests) comparing all pyramidal cells to all interneurons.


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Other Hippocampus CA1 Stratum radiatum - L/M interneurons resting membrane potential (mV) -60.0 ± 0.9 (35) -60.0 (mV) Data Table
Other Hippocampus CA1 Stratum radiatum - L/M interneurons spike peak (mV) 20.0 ± 1.4 (35) 20.0 (mV) Data Table
Other Hippocampus CA1 Stratum radiatum - L/M interneurons spike threshold (mV) -45.0 ± 0.7 (35) -45.0 (mV) Data Table
Other Hippocampus CA1 Stratum radiatum - L/M interneurons input resistance (MΩ) 279.0 ± 15.0 (35) 279.0 (MΩ) Data Table
Other Hippocampus CA1 Stratum radiatum - L/M interneurons spike half-width (ms) 1.2 ± 0.1 (35) 1.2 (ms) Data Table
Other Hippocampus CA1 Stratum Oriens Interneuron resting membrane potential (mV) -57.0 ± 1.0 (19) -57.0 (mV) Data Table
Other Hippocampus CA1 Stratum Oriens Interneuron spike peak (mV) 24.0 ± 2.0 (19) 24.0 (mV) Data Table
Other Hippocampus CA1 Stratum Oriens Interneuron spike threshold (mV) -47.0 ± 0.8 (19) -47.0 (mV) Data Table
Other Hippocampus CA1 Stratum Oriens Interneuron input resistance (MΩ) 272.0 ± 25.0 (19) 272.0 (MΩ) Data Table
Other Hippocampus CA1 Stratum Oriens Interneuron spike half-width (ms) 1.1 ± 0.1 (19) 1.1 (ms) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -63.0 ± 1.0 (32) -63.0 (mV) Data Table
Hippocampus CA1 pyramidal cell spike peak (mV) 42.0 ± 2.0 (32) 42.0 (mV) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 70.6 ± 4.0 (32) 70.6 (MΩ) Data Table
Hippocampus CA1 pyramidal cell spike half-width (ms) 1.3 ± 0.04 (32) 1.3 (ms) Data Table