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Article: Reduced glycine transporter type 1 expression leads to major changes in glutamatergic neurotransmission of CA1 hippocampal neurones in mice.

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Martina M; B-Turcotte ME; Halman S; Tsai G; Tiberi M; Coyle JT; Bergeron R
J. Physiol. (Lond.), 2005


Table 2. 

Physiological properties of WT and GlyT1+/− CA1 pyramidal cells

Genotype Vm (mV) Rin (mΩ) Spike amplitude (mV) τ (ms) Spike duration at half amplitude (ms)
Values are mean ± s.e.m.
WT −75.93 ± 0.77 199.31 ± 7.93 95.17 ± 1.93 27.20 ± 1.94 2.08 ± 0.08
n = 28 n = 28 n = 28 n = 28 n = 28
GlyT1+/− −78.25 ± 0.53 183.07 ± 13.69 99.54 ± 2.14 22.10 ± 1.52 1.89 ± 0.10
n = 15 n = 15 n = 15 n = 15 n = 15

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -75.93 ± 0.77 (28) -75.93 (mV) Data Table
Hippocampus CA1 pyramidal cell input resistance (mΩ) 199.31 ± 7.93 (28) 199.31 (MΩ) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 95.17 ± 1.93 (28) 95.17 (mV) Data Table
Hippocampus CA1 pyramidal cell membrane time constant (ms) 27.2 ± 1.94 (28) 27.2 (ms) Data Table
Hippocampus CA1 pyramidal cell spike half-width (ms) 2.08 ± 0.08 (28) 2.08 (ms) Data Table