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Article: Hypertension induced by angiotensin II and a high salt diet involves reduced SK current and increased excitability of RVLM projecting PVN neurons.

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Chen QH; Andrade MA; Calderon AS; Toney GM
J. Neurophysiol., 2010


Table 1.

Passive membrane properties of PVN-RVLM neurons

Group n Vm, mV Rinput, GΩ Cm, pF
NT-control 8 −62 ± 2 1.2 ± 0.1 25 ± 2
NT-apamin 8 −63 ± 2 1.2 ± 0.1 24 ± 2
HT-control 10 −66 ± 2 1.3 ± 0.1 28 ± 2
HT-apamin 7 −60 ± 2 1.3 ± 0.1 23 ± 2

  • PVN-RVLM, paraventricular nucleus - rostral ventrolateral medulla; Vm, resting membrane potential; Cm, membrane capacitance; Rinput, input resistance; NT, normotensive; HT, hypotensive.


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Paraventricular hypothalamic nucleus neurons Paraventricular Nucleus Rostral Ventrolateral Medulla Hypotensive Neuron resting membrane potential (mV) -66.0 ± 2.0 (10) -66.0 (mV) Data Table
Paraventricular hypothalamic nucleus neurons Paraventricular Nucleus Rostral Ventrolateral Medulla Hypotensive Neuron input resistance (GΩ) 1.3 ± 0.1 (10) 1300.0 (MΩ) Data Table
Paraventricular hypothalamic nucleus neurons Paraventricular Nucleus Rostral Ventrolateral Medulla Hypotensive Neuron cell capacitance (pF) 28.0 ± 2.0 (10) 28.0 (pF) Data Table
Paraventricular hypothalamic nucleus neurons Paraventricular Nucleus Rostral Ventrolateral Medulla Normotensive Neuron resting membrane potential (mV) -62.0 ± 2.0 (8) -62.0 (mV) Data Table
Paraventricular hypothalamic nucleus neurons Paraventricular Nucleus Rostral Ventrolateral Medulla Normotensive Neuron input resistance (GΩ) 1.2 ± 0.1 (8) 1200.0 (MΩ) Data Table
Paraventricular hypothalamic nucleus neurons Paraventricular Nucleus Rostral Ventrolateral Medulla Normotensive Neuron cell capacitance (pF) 25.0 ± 2.0 (8) 25.0 (pF) Data Table