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Article: Increased excitatory synaptic input to granule cells from hilar and CA3 regions in a rat model of temporal lobe epilepsy.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Zhang W; Huguenard JR; Buckmaster PS J. Neurosci., 2012
Table 1.
Intrinsic electrophysiological properties of normotopic granule cells in control and epileptic rats
| Control | Epileptic | |
|---|---|---|
| n (cells) | 32 | 37 |
| Resting membrane potential (mV) | −71 ± 1 | −71 ± 1 |
| Input resistance (MΩ) | 310 ± 19 | 272 ± 15 |
| Membrane time constant (ms) | 22 ± 2 | 25 ± 1 |
| Action potential threshold (mV) | −32 ± 1 | −34 ± 1 |
| Action potential amplitude (mV) | 125 ± 2 | 125 ± 2 |
| Action potential frequency (Hz at 200 pA) | 18 ± 2 | 19 ± 1 |
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Values indicate mean ± SEM. There were no statistically significant differences.
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Dentate gyrus granule cell | membrane time constant (ms) | 22.0 ± 2.0 | 22.0 (ms) | Data Table | |
| Dentate gyrus granule cell | spike threshold (mV) | -32.0 ± 1.0 | -32.0 (mV) | Data Table | |
| Dentate gyrus granule cell | firing frequency | 18.0 ± 2.0 | 18.0 (Hz) | Data Table | |
| Dentate gyrus granule cell | resting membrane potential (mV) | -71.0 ± 1.0 | -71.0 (mV) | Data Table | |
| Dentate gyrus granule cell | input resistance (MΩ) | 310.0 ± 19.0 | 310.0 (MΩ) | Data Table |