AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Distinct Physiological Effects of Dopamine D4 Receptors on Prefrontal Cortical Pyramidal Neurons and Fast-Spiking Interneurons.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Zhong P; Yan Z
Cereb. Cortex, 2014


Table 1

Membrane properties and spontaneous AP properties in PFC pyramidal neurons and PV+ interneurons

PFC pyramidal neuron PFC PV+ interneuron
Resting potential (mV) -63.8 ± 0.8 -69.5 ± 1.9
Spike threshold (mV) -45.9 ± 0.9 -46.1 ± 1.0
Input resistance (MΩ) 238.2 ± 10.3 147.7 ± 8.8*
Spike amplitude (mV) 84.3 ± 1.8 65.3 ± 2.1*
Spike halfwidth (ms) 1.8 ± 0.1 0.8 ± 0.1*
Membrane capacitance (pF) 63.2 ± 2.1 36.2 ± 1.7*
Cell number 11 12

  • *P < 0.05, K-W test.


Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 large pyramidal neuron spike amplitude (mV) 84.3 ± 1.8 (11) 84.3 (mV) Data Table
Neocortex basket cell Prefrontal cortex Parvalbumin-positive fast-spiking interneuron spike amplitude (mV) 65.3 ± 2.1 (12) 65.3 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 large pyramidal neuron spike half-width (ms) 1.8 ± 0.1 (11) 1.8 (ms) Data Table
Neocortex basket cell Prefrontal cortex Parvalbumin-positive fast-spiking interneuron spike half-width (ms) 0.8 ± 0.1 (12) 0.8 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 large pyramidal neuron cell capacitance (pF) 63.2 ± 2.1 (11) 63.2 (pF) Data Table
Neocortex basket cell Prefrontal cortex Parvalbumin-positive fast-spiking interneuron cell capacitance (pF) 36.2 ± 1.7 (12) 36.2 (pF) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 large pyramidal neuron resting membrane potential (mV) -63.8 ± 0.8 (11) -63.8 (mV) Data Table
Neocortex basket cell Prefrontal cortex Parvalbumin-positive fast-spiking interneuron resting membrane potential (mV) -69.5 ± 1.9 (12) -69.5 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 large pyramidal neuron spike threshold (mV) -45.9 ± 0.9 (11) -45.9 (mV) Data Table
Neocortex basket cell Prefrontal cortex Parvalbumin-positive fast-spiking interneuron spike threshold (mV) -46.1 ± 1.0 (12) -46.1 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Prefrontal cortex layer 5 large pyramidal neuron input resistance (MΩ) 238.2 ± 10.3 (11) 238.2 (MΩ) Data Table
Neocortex basket cell Prefrontal cortex Parvalbumin-positive fast-spiking interneuron input resistance (MΩ) 147.7 ± 8.8 (12) 147.7 (MΩ) Data Table