AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Homeostatic dysregulation in membrane properties of masticatory motoneurons compared with oculomotor neurons in a mouse model for amyotrophic lateral sclerosis.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Venugopal S; Hsiao CF; Sonoda T; Wiedau-Pazos M; Chandler SH
J. Neurosci., 2015


Table 2.

Membrane properties of WT and SOD1G93A OMNs classified by predicted MU type

Membrane property PS PF
WT (n = 10) SOD1G93A (n = 9) WT (n = 11) SOD1G93A (n = 8)
Cm, pF 114.2 ± 8.6 105.1 ± 7.7 161.1 ± 10.4 163.3 ± 10.1
Rinp, MΩ 97.3 ± 10.6 123.5 ± 16.5 37.2 ± 3.5 47.0 ± 4.5
RMP, mV -56.9 ± 1.8 -57.9 ± 1.3 -59.1 ± 1.2 -59.3 ± 1.0
Rheobase, pA 162.0 ± 17.3 113.9 ± 20.0 400.0 ± 27.0 368.8 ± 32.6
AP threshold, mV -43.7 ± 1.9 -42.4 ± 2.0 -40.8 ± 1.7 -40.5 ± 1.4
AP height, mV 88 ± 3.6 87.6 ± 2.3 93.7 ± 1.8 92.0 ± 2.9
AP half-width, ms 0.9 ± 0.1 1.0 ± 0.1 0.7 ± 0.03 0.7 ± 0.04
AHP, mV -4.7 ± 1.2 -7.2 ± 1.6 -2.8 ± 0.3 -2.6 ± 0.4

  • Values reported as mean ± SEM. Student t tests were performed for statistical comparison between WT and SOD1G93A neurons within the two predicted MU types.


Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Oculomotor nucleus motor neuron oculomotor nucleus predicted slow firing motor neuron cell capacitance (pF) 114.2 ± 8.6 (10) 114.2 (pF) Data Table
Oculomotor nucleus motor neuron oculomotor nucleus predicted fast firing motor neuron cell capacitance (pF) 161.1 ± 10.4 (11) 161.1 (pF) Data Table
Oculomotor nucleus motor neuron oculomotor nucleus predicted slow firing motor neuron input resistance (MΩ) 97.3 ± 10.6 (10) 97.3 (MΩ) Data Table
Oculomotor nucleus motor neuron oculomotor nucleus predicted fast firing motor neuron input resistance (MΩ) 37.2 ± 3.5 (11) 37.2 (MΩ) Data Table
Oculomotor nucleus motor neuron oculomotor nucleus predicted slow firing motor neuron resting membrane potential (mV) -56.9 ± 1.8 (10) -56.9 (mV) Data Table
Oculomotor nucleus motor neuron oculomotor nucleus predicted fast firing motor neuron resting membrane potential (mV) -59.1 ± 1.2 (11) -59.1 (mV) Data Table
Oculomotor nucleus motor neuron oculomotor nucleus predicted slow firing motor neuron rheobase (pA) 162.0 ± 17.3 (10) 162.0 (pA) Data Table
Oculomotor nucleus motor neuron oculomotor nucleus predicted fast firing motor neuron rheobase (pA) 400.0 ± 27.0 (11) 400.0 (pA) Data Table
Oculomotor nucleus motor neuron oculomotor nucleus predicted slow firing motor neuron spike threshold (mV) -43.7 ± 1.9 (10) -43.7 (mV) Data Table
Oculomotor nucleus motor neuron oculomotor nucleus predicted fast firing motor neuron spike threshold (mV) -40.8 ± 1.7 (11) -40.8 (mV) Data Table
Oculomotor nucleus motor neuron oculomotor nucleus predicted slow firing motor neuron spike amplitude (mV) 88.0 ± 3.6 (10) 88.0 (mV) Data Table
Oculomotor nucleus motor neuron oculomotor nucleus predicted fast firing motor neuron spike amplitude (mV) 93.7 ± 1.8 (11) 93.7 (mV) Data Table
Oculomotor nucleus motor neuron oculomotor nucleus predicted slow firing motor neuron spike half-width (ms) 0.9 ± 0.1 (10) 0.9 (ms) Data Table
Oculomotor nucleus motor neuron oculomotor nucleus predicted fast firing motor neuron spike half-width (ms) 0.7 ± 0.03 (11) 0.7 (ms) Data Table
Oculomotor nucleus motor neuron oculomotor nucleus predicted slow firing motor neuron AHP amplitude (mV) -4.7 ± 1.2 (10) 4.7 (mV) Data Table
Oculomotor nucleus motor neuron oculomotor nucleus predicted fast firing motor neuron AHP amplitude (mV) -2.8 ± 0.3 (11) 2.8 (mV) Data Table