Article: Reversal of Aging-Related Neuronal Ca2+ Dysregulation and Cognitive Impairment by Delivery of a Transgene Encoding FK506-Binding Protein 12.6/1b to the Hippocampus.

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Gant JC; Chen KC; Kadish I; Blalock EM; Thibault O; Porter NM; Landfield PW
J. Neurosci., 2015

Table 1.

Baseline electrophysiological measures for neurons from behaviorally characterized rats (means ± SEM)

	Aged-FKBP1b	Aged-Control	Young	F value	p value
N animals	7	6	5
n neurons	17	16	13
Resting potential (mV)	-59.88 ± 0.74	-59.44 ± 0.75	-59.39 ± 0.70	0.14	0.87
Input resistance (MΩ)	56.29 ± 2.02	53.81 ± 2.65	53.85 ± 3.92	0.27	0.76
AP height (mV)	83.91 ± 1.34	86.28 ± 1.47	87.94 ± 2.24	1.50	0.24

Inferred neuron-electrophysiology data values

Neuron Type	Ephys Prop	Extracted Value	Standardized Value	Content Source
Hippocampus CA1 pyramidal cell	resting membrane potential (mV)	-59.44 ± 0.75 (16)	-59.44 (mV)	Data Table
Hippocampus CA1 pyramidal cell	resting membrane potential (mV)	-59.39 ± 0.7 (13)	-59.39 (mV)	Data Table
Hippocampus CA1 pyramidal cell	input resistance (MΩ)	53.81 ± 2.65 (16)	53.81 (MΩ)	Data Table
Hippocampus CA1 pyramidal cell	input resistance (MΩ)	53.85 ± 3.92 (13)	53.85 (MΩ)	Data Table
Hippocampus CA1 pyramidal cell	spike amplitude (mV)	86.28 ± 1.47 (16)	86.28 (mV)	Data Table
Hippocampus CA1 pyramidal cell	spike amplitude (mV)	87.94 ± 2.24 (13)	87.94 (mV)	Data Table