NeuroElectro Publications

Article: Effects of ethanol on rat somatosensory cortical neurons.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Sessler FM; Hsu FC; Felder TN; Zhai J; Lin RC; Wieland SJ; Kosobud AE
Brain Res., 1998

	N	Layer V neurons	N	Layer II-III neurons
Resting membrane potential (mV)	37	-68.3±0.95	28	-76.0±1.3***
Input resistance (MΩ)	37	31.9±2.0	20	34.2±2.3
Rheobase (nA)	37	0.41±0.04	28	0.56±0.04**
Time constant (ms)	32	6.52±0.33	15	9.54±0.83***
Relative threshold for spiking (mV)	22	17.5±1.6	10	26.3±3.2**
Absolute threshold for spiking (mV)	18	-51.8±1.1	10	-51.1±2.8
Spike amplitude (mV)	20	85.2±2.7	10	86.2±3.1
Spike area (ms mV)	20	54.4±4.1	10	75.7±4.4**
Spike peak latency (ms)	20	0.28±0.01	10	0.36±0.02**
Spike width (at 1/2 amplitude) (ms)	20	0.64±0.04	10	0.84±0.04**
Spike rise time (10-90%) (ms)	20	0.15±0.01	10	0.18±0.01*
PSP latency (ms)	17	2.22±0.27	12	1.93±0.11
PSP rise time (10-90%) (ms)	17	4.4±0.8	12	3.2±0.24
PSP early peak latency (ms)	17	6.0±1.04	12	5.55±0.39
PSP late peak latency (ms)	12	14.6±2.02	11	17.6±0.86
PSP early peak amplitude (mV)	17	11.5±1.38	12	20.6±1.55***
PSP late peak amplitude (mV)	11	6.67±0.66	12	7.86±0.9
PSP area (ms mV)	16	265±40	12	447±43**
PSP width (at half amplitude) (ms)	17	16.9±1.6	14	14.4±1.71

Inferred neuron-electrophysiology data values

Neuron Type	Neuron Description	Ephys Prop	Extracted Value	Standardized Value	Content Source
Neocortex pyramidal cell layer 2-3	Somatosensory cortex layer 2-3 pyramidal neurons	input resistance (MΩ)	34.2 ± 2.3 (10)	34.2 (MΩ)	Data Table
Neocortex pyramidal cell layer 5-6	Somatosensory cortex layer 5 pyramidal neurons	rheobase (nA)	0.41 ± 0.04 (20)	410.0 (pA)	Data Table
Neocortex pyramidal cell layer 2-3	Somatosensory cortex layer 2-3 pyramidal neurons	rheobase (nA)	0.56 ± 0.04 (10)	560.0 (pA)	Data Table
Neocortex pyramidal cell layer 5-6	Somatosensory cortex layer 5 pyramidal neurons	membrane time constant (ms)	6.52 ± 0.33 (20)	6.52 (ms)	Data Table
Neocortex pyramidal cell layer 2-3	Somatosensory cortex layer 2-3 pyramidal neurons	membrane time constant (ms)	9.54 ± 0.83 (10)	9.54 (ms)	Data Table
Neocortex pyramidal cell layer 5-6	Somatosensory cortex layer 5 pyramidal neurons	spike threshold (mV)	-51.8 ± 1.1 (20)	-51.8 (mV)	Data Table
Neocortex pyramidal cell layer 5-6	Somatosensory cortex layer 5 pyramidal neurons	resting membrane potential (mV)	-68.3 ± 0.95 (20)	-68.3 (mV)	Data Table
Neocortex pyramidal cell layer 2-3	Somatosensory cortex layer 2-3 pyramidal neurons	spike threshold (mV)	-51.1 ± 2.8 (10)	-51.1 (mV)	Data Table
Neocortex pyramidal cell layer 5-6	Somatosensory cortex layer 5 pyramidal neurons	spike amplitude from resting (mV)	85.2 ± 2.7 (20)	85.2 (mV)	Data Table
Neocortex pyramidal cell layer 2-3	Somatosensory cortex layer 2-3 pyramidal neurons	spike amplitude from resting (mV)	86.2 ± 3.1 (10)	86.2 (mV)	Data Table
Neocortex pyramidal cell layer 5-6	Somatosensory cortex layer 5 pyramidal neurons	first spike latency (ms)	0.28 ± 0.01 (20)	0.28 (ms)	Data Table
Neocortex pyramidal cell layer 2-3	Somatosensory cortex layer 2-3 pyramidal neurons	first spike latency (ms)	0.36 ± 0.02 (10)	0.36 (ms)	Data Table
Neocortex pyramidal cell layer 5-6	Somatosensory cortex layer 5 pyramidal neurons	spike half-width	0.64 ± 0.04 (20)	0.64 (ms)	Data Table
Neocortex pyramidal cell layer 2-3	Somatosensory cortex layer 2-3 pyramidal neurons	resting membrane potential (mV)	-76.0 ± 1.3 (10)	-76.0 (mV)	Data Table
Neocortex pyramidal cell layer 2-3	Somatosensory cortex layer 2-3 pyramidal neurons	spike half-width	0.84 ± 0.04 (10)	0.84 (ms)	Data Table
Neocortex pyramidal cell layer 5-6	Somatosensory cortex layer 5 pyramidal neurons	spike rise time	0.15 ± 0.01 (20)	0.15 (ms)	Data Table
Neocortex pyramidal cell layer 2-3	Somatosensory cortex layer 2-3 pyramidal neurons	spike rise time	0.18 ± 0.01 (10)	0.18 (ms)	Data Table
Neocortex pyramidal cell layer 5-6	Somatosensory cortex layer 5 pyramidal neurons	input resistance (MΩ)	31.9 ± 2.0 (20)	31.9 (MΩ)	Data Table