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Article: Slowly inactivating component of Na+ current in peri-somatic region of hippocampal CA1 pyramidal neurons.

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Park YY; Johnston D; Gray R
J. Neurophysiol., 2013


Table 2.

Change in physiological parameters in the presence of hexanol

BaselineHexanolP Value
Input resistance, MΩ67.6 ± 3.465.4 ± 3.30.29
Spike threshold, mV-43.27 ± 1.54-38.68 ± 2.180.0033†
Spike peak dV/dt, mV/ms259.8 ± 19.5233.9 ± 14.40.19
Spike width, ms1.40 ± 0.091.37 ± 0.080.34
Spike amplitude, mV100.4 ± 2.598.9 ± 1.50.44
No. of spikes by a 700-ms step current injection of 150 pA8.0 ± 1.94.4 ± 2.10.0061†
No. of spikes by 5 α-EPSP injections at 25 Hz2.9 ± 0.21.1 ± 0.40.0077†
1st spike latency, ms171.4 ± 22.6392.1 ± 71.30.016*

  • Values are means ± SE (n = 5). Spike threshold was defined as a membrane voltage where dV/dt = 20 mV/ms. Spike amplitude was calculated by Vpeak - Vrest. Paired t-test:

  • ↵* P < 0.05;

  • ↵† P < 0.01.


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell input resistance (MΩ) 67.6 ± 3.4 67.6 (MΩ) Data Table
Hippocampus CA1 pyramidal cell spike threshold (mV) -43.27 ± 1.54 -43.27 (mV) Data Table
Hippocampus CA1 pyramidal cell spike max rise slope (mV/ms) 259.8 ± 19.5 259.8 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell spike half-width (ms) 1.4 ± 0.09 1.4 (ms) Data Table
Hippocampus CA1 pyramidal cell spike amplitude from resting (mV) 100.4 ± 2.5 100.4 (mV) Data Table
Hippocampus CA1 pyramidal cell first spike latency (ms) 171.4 ± 22.6 171.4 (ms) Data Table