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Article: GCP II (NAALADase) inhibition suppresses mossy fiber-CA3 synaptic neurotransmission by a presynaptic mechanism.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Sanabria ER; Wozniak KM; Slusher BS; Keller A
J. Neurophysiol., 2004

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA3 pyramidal cell ADP amplitude (mV) 3.3 ± 0.9 (7) 3.3 (mV) Data Table
Hippocampus CA3 pyramidal cell fast AHP amplitude 4.5 ± 0.5 (7) 4.5 (mV) Data Table
Hippocampus CA3 pyramidal cell input resistance (MΩ) 223.8 ± 7.1 (7) 223.8 (MΩ) Data Table
Hippocampus CA3 pyramidal cell membrane time constant (ms) 45.8 ± 7.1 (7) 45.8 (ms) Data Table
Hippocampus CA3 pyramidal cell resting membrane potential (mV) -64.2 ± 1.9 (7) -64.2 (mV) Data Table
Hippocampus CA3 pyramidal cell rheobase (pA) 98.9 ± 1.8 (7) 98.9 (pA) Data Table
Hippocampus CA3 pyramidal cell spike amplitude from resting (mV) 105.7 ± 5.3 (7) 105.7 (mV) Data Table
Hippocampus CA3 pyramidal cell spike threshold (mV) -42.4 ± 3.1 (7) -42.4 (mV) Data Table

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Metadata values

Experimental condition Value
Species Rats
ElectrodeType Patch-clamp
Strain Wistar
PrepType in vitro
JxnPotential Unreported
AnimalAge 21.0 - 30.0
RecTemp 32.0
InternalSolution 5.0
ExternalSolution 5.0
internal_0_pH 7.2
internal_0_Mg 3.5
internal_0_Na 0.5
internal_0_K 130.0
internal_0_GTP 0.25
internal_0_BAPTA 0.1
internal_0_ATP 2.5
internal_0_HEPES 10.0
internal_0_Cl 12.0
external_0_pH 7.4
external_0_Mg 2.0
external_0_Na 125.0
external_0_K 3.0
external_0_Cl 132.0
external_0_Ca 2.0
external_0_glucose 15.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
769 GCP II (NAALADase) inhibition suppresses mossy fiber-CA3 synaptic neurotransmission by a presynaptic mechanism. Sanabria ER; Wozniak KM; Slusher BS; Keller A J. Neurophysiol. 2004 False 8 Shreejoy Tripathy, Ryan Sefidpour, Nathalie Binnion, James liu, Patrick Savage, 4