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Article: Spatial Gene-Expression Gradients Underlie Prominent Heterogeneity of CA1 Pyramidal Neurons.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Cembrowski MS; Bachman JL; Wang L; Sugino K; Shields BC; Spruston N
Neuron, 2016

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell Dorsal Hippocampus CA1 pyramidal cell ADP amplitude (mV) 28.3 ± 0.4 (46) 28.3 (mV) Data Table
Hippocampus CA1 pyramidal cell Ventral Hippocampus CA1 pyramidal cell ADP amplitude (mV) 29.6 ± 0.7 (31) 29.6 (mV) Data Table
Hippocampus CA1 pyramidal cell Ventral Hippocampus CA1 pyramidal cell AHP amplitude (mV) -0.931 ± 0.04 (31) 0.931 (mV) Data Table
Hippocampus CA1 pyramidal cell Dorsal Hippocampus CA1 pyramidal cell AHP amplitude (mV) -0.776 ± 0.024 (46) 0.776 (mV) Data Table
Hippocampus CA1 pyramidal cell Ventral Hippocampus CA1 pyramidal cell input resistance 179.0 ± 15.0 (31) 179.0 (MΩ) Data Table
Hippocampus CA1 pyramidal cell Dorsal Hippocampus CA1 pyramidal cell input resistance 107.0 ± 3.0 (46) 107.0 (MΩ) Data Table
Hippocampus CA1 pyramidal cell Ventral Hippocampus CA1 pyramidal cell resting membrane potential (mV) -68.6 ± 0.5 (31) -68.6 (mV) Data Table
Hippocampus CA1 pyramidal cell Dorsal Hippocampus CA1 pyramidal cell resting membrane potential (mV) -66.6 ± 0.3 (46) -66.6 (mV) Data Table
Hippocampus CA1 pyramidal cell Dorsal Hippocampus CA1 pyramidal cell sag ratio 0.709 ± 0.004 (46) 0.709 (ratio) Data Table
Hippocampus CA1 pyramidal cell Ventral Hippocampus CA1 pyramidal cell sag ratio 0.734 ± 0.008 (31) 0.734 (ratio) Data Table
Hippocampus CA1 pyramidal cell Ventral Hippocampus CA1 pyramidal cell spike amplitude (mV) 95.8 ± 0.7 (31) 95.8 (mV) Data Table
Hippocampus CA1 pyramidal cell Dorsal Hippocampus CA1 pyramidal cell spike amplitude (mV) 98.1 ± 0.5 (46) 98.1 (mV) Data Table
Hippocampus CA1 pyramidal cell Ventral Hippocampus CA1 pyramidal cell spike half-width (ms) 0.895 ± 0.017 (31) 0.895 (ms) Data Table
Hippocampus CA1 pyramidal cell Dorsal Hippocampus CA1 pyramidal cell spike half-width (ms) 0.901 ± 0.001 (46) 0.901 (ms) Data Table
Hippocampus CA1 pyramidal cell Dorsal Hippocampus CA1 pyramidal cell spike max decay slope (mV/ms) -112.0 ± 1.0 (46) 112.0 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell Ventral Hippocampus CA1 pyramidal cell spike max decay slope (mV/ms) -116.0 ± 1.0 (31) 116.0 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell Dorsal Hippocampus CA1 pyramidal cell spike max rise slope (mV/ms) 662.0 ± 12.0 (46) 662.0 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell Ventral Hippocampus CA1 pyramidal cell spike max rise slope (mV/ms) 656.0 ± 17.0 (31) 656.0 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell Dorsal Hippocampus CA1 pyramidal cell spike threshold (mV) -52.4 ± 0.4 (46) -52.4 (mV) Data Table
Hippocampus CA1 pyramidal cell Ventral Hippocampus CA1 pyramidal cell spike threshold (mV) -50.2 ± 8.0 (31) -50.2 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
Species Mice
Strain Mice, Transgenic
ElectrodeType Patch-clamp
PrepType in vitro
JxnPotential Unreported
AnimalAge 21.0 - 28.0
RecTemp 32.0 - 35.0
InternalSolution 5.0
ExternalSolution 5.0
internal_0_pH 7.35
internal_0_Mg 2.0
internal_0_Na 10.3
internal_0_K 135.0
internal_0_GTP 0.1
internal_0_ATP 2.0
internal_0_HEPES 10.0
internal_0_Cl 20.0
external_0_Mg 1.0
external_0_Na 151.25
external_0_K 2.5
external_0_Cl 133.5
external_0_Ca 2.0
external_0_glucose 25.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
50019 Spatial Gene-Expression Gradients Underlie Prominent Heterogeneity of CA1 Pyramidal Neurons. Cembrowski MS; Bachman JL; Wang L; Sugino K; Shields BC; Spruston N Neuron 2016 False 10 Brenna Li, Ryan Sefidpour, 1