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Article: Secondhand smoke exposure alters K+ channel function and intrinsic cell excitability in a subset of second-order airway neurons in the nucleus tractus solitarius of young guinea pigs.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Sekizawa S; Joad JP; Pinkerton KE; Bonham AC
Eur. J. Neurosci., 2010

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Nucleus of the solitary tract principal cell cell capacitance (pF) 69.6 ± 7.4 (17) 69.6 (pF) Data Table
Nucleus of the solitary tract principal cell input resistance (MΩ) 141.7 ± 18.4 (17) 141.7 (MΩ) Data Table
Nucleus of the solitary tract principal cell membrane time constant (ms) 9.0 ± 1.1 (17) 9.0 (ms) Data Table
Nucleus of the solitary tract principal cell resting membrane potential (mV) -47.6 ± 1.9 (17) -47.6 (mV) Data Table
Nucleus of the solitary tract principal cell spike amplitude from resting (mV) 83.7 ± 4.5 (17) 83.7 (mV) Data Table
Nucleus of the solitary tract principal cell spike threshold (mV) -42.3 ± 1.2 (17) -42.3 (mV) Data Table
Nucleus of the solitary tract intrinsic cell cell capacitance (pF) 116.0 ± 26.6 (7) 116.0 (pF) Data Table
Nucleus of the solitary tract intrinsic cell input resistance (MΩ) 103.5 ± 15.9 (7) 103.5 (MΩ) Data Table
Nucleus of the solitary tract intrinsic cell membrane time constant (ms) 11.5 ± 2.9 (7) 11.5 (ms) Data Table
Nucleus of the solitary tract intrinsic cell resting membrane potential (mV) -47.4 ± 5.0 (7) -47.4 (mV) Data Table
Nucleus of the solitary tract intrinsic cell spike amplitude from resting (mV) 100.6 ± 6.5 (7) 100.6 (mV) Data Table
Nucleus of the solitary tract intrinsic cell spike threshold (mV) -38.8 ± 0.7 (7) -38.8 (mV) Data Table

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Metadata values

Experimental condition Value
ElectrodeType Patch-clamp
PrepType in vitro
Species Guinea Pigs
RecTemp 33.0 - 34.0
InternalSolution 5.0
ExternalSolution 5.0
AnimalAge 46.5 ± 0.9
Strain Other
JxnPotential Unreported
internal_0_pH 7.4
internal_0_Mg 1.0
internal_0_Na 5.2
internal_0_K 143.0
internal_0_GTP 0.2
internal_0_ATP 3.0
internal_0_EGTA 10.0
internal_0_HEPES 10.0
internal_0_Cl 147.0
external_0_pH 7.4
external_0_Mg 1.0
external_0_Na 151.25
external_0_K 2.5
external_0_Cl 133.5
external_0_Ca 2.0
external_0_glucose 25.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
20244 Secondhand smoke exposure alters K+ channel function and intrinsic cell excitability in a subset of second-order airway neurons in the nucleus tractus solitarius of young guinea pigs. Sekizawa S; Joad JP; Pinkerton KE; Bonham AC Eur. J. Neurosci. 2010 False 6 Shreejoy Tripathy, Kerrie Tsigounis, Brenna Li, 1
20245 Secondhand smoke exposure alters K+ channel function and intrinsic cell excitability in a subset of second-order airway neurons in the nucleus tractus solitarius of young guinea pigs. Sekizawa S; Joad JP; Pinkerton KE; Bonham AC Eur. J. Neurosci. 2010 False 6 Shreejoy Tripathy, Brenna Li, Ryan Sefidpour, Kerrie Tsigounis, James liu, 6
20246 Secondhand smoke exposure alters K+ channel function and intrinsic cell excitability in a subset of second-order airway neurons in the nucleus tractus solitarius of young guinea pigs. Sekizawa S; Joad JP; Pinkerton KE; Bonham AC Eur. J. Neurosci. 2010 False 0 None