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Article: Dopamine increases inhibition in the monkey dorsolateral prefrontal cortex through cell type-specific modulation of interneurons.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Kröner S; Krimer LS; Lewis DA; Barrionuevo G
Cereb. Cortex, 2007

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 adapting non-pyramidal GABAergic interneurons AHP amplitude (mV) 16.1 ± 0.9 16.1 (mV) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 pyramidal fast-spiking GABAergic interneuron AHP amplitude (mV) 23.8 ± 0.7 23.8 (mV) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 adapting non-pyramidal GABAergic interneurons AHP duration (mV) 3.53 ± 0.76 -- Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 pyramidal fast-spiking GABAergic interneuron AHP duration (mV) 1.45 ± 0.14 -- Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 pyramidal fast-spiking GABAergic interneuron input resistance (MΩ) 191.9 ± 17.1 191.9 (MΩ) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 adapting non-pyramidal GABAergic interneurons input resistance (MΩ) 281.7 ± 31.1 281.7 (MΩ) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 pyramidal fast-spiking GABAergic interneuron membrane time constant (ms) 10.7 ± 1.0 10.7 (ms) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 adapting non-pyramidal GABAergic interneurons membrane time constant (ms) 21.7 ± 2.1 21.7 (ms) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 adapting non-pyramidal GABAergic interneurons resting membrane potential (mV) -68.0 ± 0.8 -68.0 (mV) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 pyramidal fast-spiking GABAergic interneuron resting membrane potential (mV) -68.7 ± 0.65 -68.7 (mV) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 adapting non-pyramidal GABAergic interneurons rheobase (pA) 54.4 ± 7.5 54.4 (pA) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 pyramidal fast-spiking GABAergic interneuron rheobase (pA) 139.5 ± 13.8 139.5 (pA) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 pyramidal fast-spiking GABAergic interneuron sag ratio 1.56 ± 0.16 1.56 (ratio) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 adapting non-pyramidal GABAergic interneurons sag ratio 2.45 ± 0.52 0.0245 (ratio) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 pyramidal fast-spiking GABAergic interneuron spike amplitude 48.9 ± 1.1 48.9 (mV) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 adapting non-pyramidal GABAergic interneurons spike amplitude 60.2 ± 2.2 60.2 (mV) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 pyramidal fast-spiking GABAergic interneuron spike decay time (ms) 0.36 ± 0.03 0.36 (ms) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 adapting non-pyramidal GABAergic interneurons spike decay time (ms) 0.69 ± 0.05 0.69 (ms) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 adapting non-pyramidal GABAergic interneurons spike half-width (ms) 0.82 ± 0.05 0.82 (ms) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 pyramidal fast-spiking GABAergic interneuron spike half-width (ms) 0.48 ± 0.03 0.48 (ms) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 pyramidal fast-spiking GABAergic interneuron spike rise time (ms) 0.31 ± 0.01 0.31 (ms) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 adapting non-pyramidal GABAergic interneurons spike rise time (ms) 0.42 ± 0.02 0.42 (ms) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 pyramidal fast-spiking GABAergic interneuron spike threshold (mV) -40.0 ± 0.9 -40.0 (mV) Data Table
Neocortex interneuron deep dorsolateral prefrontal cortex layer 2/3 adapting non-pyramidal GABAergic interneurons spike threshold (mV) -43.5 ± 0.9 -43.5 (mV) Data Table
Neocortex pyramidal cell layer 2-3 dorsolateral prefrontal cortex layer 2/3 GABAergic small pyramidal neuron AHP amplitude (mV) 11.6 ± 0.9 11.6 (mV) Data Table
Neocortex pyramidal cell layer 2-3 dorsolateral prefrontal cortex layer 2/3 GABAergic small pyramidal neuron AHP duration (mV) 3.96 ± 1.41 -- Data Table
Neocortex pyramidal cell layer 2-3 dorsolateral prefrontal cortex layer 2/3 GABAergic small pyramidal neuron input resistance (MΩ) 111.2 ± 8.7 111.2 (MΩ) Data Table
Neocortex pyramidal cell layer 2-3 dorsolateral prefrontal cortex layer 2/3 GABAergic small pyramidal neuron membrane time constant (ms) 22.8 ± 2.9 22.8 (ms) Data Table
Neocortex pyramidal cell layer 2-3 dorsolateral prefrontal cortex layer 2/3 GABAergic small pyramidal neuron resting membrane potential (mV) -71.1 ± 0.92 -71.1 (mV) Data Table
Neocortex pyramidal cell layer 2-3 dorsolateral prefrontal cortex layer 2/3 GABAergic small pyramidal neuron rheobase (pA) 109.5 ± 17.0 109.5 (pA) Data Table
Neocortex pyramidal cell layer 2-3 dorsolateral prefrontal cortex layer 2/3 GABAergic small pyramidal neuron sag ratio 2.15 ± 0.21 0.0215 (ratio) Data Table
Neocortex pyramidal cell layer 2-3 dorsolateral prefrontal cortex layer 2/3 GABAergic small pyramidal neuron spike amplitude 73.2 ± 1.4 73.2 (mV) Data Table
Neocortex pyramidal cell layer 2-3 dorsolateral prefrontal cortex layer 2/3 GABAergic small pyramidal neuron spike decay time (ms) 0.93 ± 0.05 0.93 (ms) Data Table
Neocortex pyramidal cell layer 2-3 dorsolateral prefrontal cortex layer 2/3 GABAergic small pyramidal neuron spike half-width (ms) 1.05 ± 0.04 1.05 (ms) Data Table
Neocortex pyramidal cell layer 2-3 dorsolateral prefrontal cortex layer 2/3 GABAergic small pyramidal neuron spike rise time (ms) 0.48 ± 0.02 0.48 (ms) Data Table
Neocortex pyramidal cell layer 2-3 dorsolateral prefrontal cortex layer 2/3 GABAergic small pyramidal neuron spike threshold (mV) -44.5 ± 0.9 -44.5 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
ElectrodeType Patch-clamp
PrepType in vitro
JxnPotential Not corrected
ExternalSolution 5.0
external_1_Mg 1.0
external_1_Ca 2.0
external_1_Na 153.4
external_1_Cl 134.5
external_1_K 2.5
InternalSolution 5.0
Species Other
RecTemp 32.0 - 33.0
AnimalAge 1460.0 - 1825.0
AnimalWeight 3500.0 - 6000.0
Strain Other
internal_0_Mg 4.0
internal_0_Na 38.3
internal_0_K 130.0
internal_0_GTP 0.3
internal_0_ATP 4.0
internal_0_EGTA 0.5
internal_0_HEPES 10.0
internal_0_Cl 20.0
external_0_Mg 1.0
external_0_Na 153.475
external_0_K 2.5
external_0_Cl 134.5
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
36070 Dopamine increases inhibition in the monkey dorsolateral prefrontal cortex through cell type-specific modulation of interneurons. Kröner S; Krimer LS; Lewis DA; Barrionuevo G Cereb. Cortex 2007 True 12 Nathalie Binnion, James liu, Brenna Li, 4
36071 Dopamine increases inhibition in the monkey dorsolateral prefrontal cortex through cell type-specific modulation of interneurons. Kröner S; Krimer LS; Lewis DA; Barrionuevo G Cereb. Cortex 2007 False 4 0