AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Hypertension induced by angiotensin II and a high salt diet involves reduced SK current and increased excitability of RVLM projecting PVN neurons.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Chen QH; Andrade MA; Calderon AS; Toney GM
J. Neurophysiol., 2010

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Paraventricular hypothalamic nucleus neurons Paraventricular Nucleus Rostral Ventrolateral Medulla Hypotensive Neuron cell capacitance (pF) 28.0 ± 2.0 (10) 28.0 (pF) Data Table
Paraventricular hypothalamic nucleus neurons Paraventricular Nucleus Rostral Ventrolateral Medulla Normotensive Neuron cell capacitance (pF) 25.0 ± 2.0 (8) 25.0 (pF) Data Table
Paraventricular hypothalamic nucleus neurons Paraventricular Nucleus Rostral Ventrolateral Medulla Hypotensive Neuron input resistance (GΩ) 1.3 ± 0.1 (10) 1300.0 (MΩ) Data Table
Paraventricular hypothalamic nucleus neurons Paraventricular Nucleus Rostral Ventrolateral Medulla Normotensive Neuron input resistance (GΩ) 1.2 ± 0.1 (8) 1200.0 (MΩ) Data Table
Paraventricular hypothalamic nucleus neurons Paraventricular Nucleus Rostral Ventrolateral Medulla Normotensive Neuron resting membrane potential (mV) -62.0 ± 2.0 (8) -62.0 (mV) Data Table
Paraventricular hypothalamic nucleus neurons Paraventricular Nucleus Rostral Ventrolateral Medulla Hypotensive Neuron resting membrane potential (mV) -66.0 ± 2.0 (10) -66.0 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
Species Rats
ElectrodeType Patch-clamp
PrepType in vitro
Strain Sprague-Dawley
InternalSolution 5.0
ExternalSolution 5.0
JxnPotential Not corrected
AnimalWeight 225.0 - 250.0
RecTemp 24.0 - 26.0
JxnOffset -15.0
internal_0_pH 7.3
internal_0_Mg 1.0
internal_0_Na 6.0
internal_0_K 135.0
internal_0_GTP 0.5
internal_0_ATP 2.0
internal_0_EGTA 0.1
internal_0_HEPES 10.0
internal_0_Cl 3.0
external_0_pH 7.4
external_0_Mg 2.0
external_0_Na 152.25
external_0_K 2.0
external_0_Cl 131.0
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
123 Hypertension induced by angiotensin II and a high salt diet involves reduced SK current and increased excitability of RVLM projecting PVN neurons. Chen QH; Andrade MA; Calderon AS; Toney GM J. Neurophysiol. 2010 False 3 Brenna Li, Ryan Sefidpour, 1