NeuroElectro Publications

Article: Dissociation of dorsal root ganglion neurons induces hyperexcitability that is maintained by increased responsiveness to cAMP and cGMP.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Zheng JH; Walters ET; Song XJ
J. Neurophysiol., 2007

Inferred neuron-electrophysiology data values

Neuron Type	Neuron Description	Ephys Prop	Extracted Value	Standardized Value	Content Source
Dorsal root ganglion cell	small dorsal root ganglion	AHP amplitude (mV)	21.4 ± 3.5 (22)	21.4 (mV)	Data Table
Dorsal root ganglion cell	small dorsal root ganglion	AHP duration (ms)	13.6 ± 3.5 (22)	13.6 (ms)	Data Table
Dorsal root ganglion cell	small dorsal root ganglion	cell capacitance (pF)	43.2 ± 1.1 (22)	43.2 (pF)	Data Table
Dorsal root ganglion cell	small dorsal root ganglion	cell diameter	20.1 ± 1.6 (22)	20.1 (um)	Data Table
Dorsal root ganglion cell	small dorsal root ganglion	firing frequency	2.05 ± 0.25 (22)	2.05 (Hz)	Data Table
Dorsal root ganglion cell	small dorsal root ganglion	input resistance (MΩ)	416.0 ± 14.0 (22)	416.0 (MΩ)	Data Table
Dorsal root ganglion cell	small dorsal root ganglion	resting membrane potential (mV)	-55.9 ± 1.5 (22)	-55.9 (mV)	Data Table
Dorsal root ganglion cell	small dorsal root ganglion	rheobase (nA)	0.34 ± 0.04 (22)	340.0 (pA)	Data Table
Dorsal root ganglion cell	small dorsal root ganglion	spike amplitude (mV)	62.1 ± 1.0 (22)	62.1 (mV)	Data Table
Dorsal root ganglion cell	small dorsal root ganglion	spike threshold (mV)	-27.2 ± 1.7 (22)	-27.2 (mV)	Data Table
Dorsal root ganglion cell	small dorsal root ganglion	spike width (ms)	3.43 ± 0.28 (22)	3.43 (ms)	Data Table

Metadata values

Experimental condition	Value
Species	Rats
Strain	Sprague-Dawley
ElectrodeType	Patch-clamp
PrepType	in vitro
JxnPotential	Unreported
AnimalWeight	120.0 - 150.0
RecTemp	22.0
InternalSolution	5.0
ExternalSolution	5.0
internal_0_pH	7.2
internal_0_Mg	4.0
internal_0_K	150.0
internal_0_ATP	2.0
internal_0_HEPES	10.0
internal_0_Cl	26.0
internal_0_Ca	1.0
external_0_pH	7.3
external_0_Mg	1.0
external_0_Na	145.5
external_0_K	3.5
external_0_HEPES	10.0
external_0_Cl	148.5
external_0_Ca	1.5
external_0_glucose	10.0

Data table listing

Data Table	Article Title	Authors	Journal	Year	Table needs expert?	Ephys table mentions	Curated by	Times validated
420	Dissociation of dorsal root ganglion neurons induces hyperexcitability that is maintained by increased responsiveness to cAMP and cGMP.	Zheng JH; Walters ET; Song XJ	J. Neurophysiol.	2007	False	11	Shreejoy Tripathy, Kerrie Tsigounis, Brenna Li, Nathalie Binnion,	2