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Article: Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Klapstein GJ; Fisher RS; Zanjani H; Cepeda C; Jokel ES; Chesselet MF; Levine MS
J. Neurophysiol., 2001

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neostriatum medium spiny neuron AHP amplitude (mV) 15.5 ± 1.0 (8) 15.5 (mV) Data Table
Neostriatum medium spiny neuron AHP amplitude (mV) 12.7 ± 0.9 (13) 12.7 (mV) Data Table
Neostriatum medium spiny neuron input resistance (MΩ) 26.7 ± 2.8 (10) 26.7 (MΩ) Data Table
Neostriatum medium spiny neuron input resistance (MΩ) 33.7 ± 3.0 (14) 33.7 (MΩ) Data Table
Neostriatum medium spiny neuron membrane time constant (ms) 17.6 ± 2.8 (18) 17.6 (ms) Data Table
Neostriatum medium spiny neuron membrane time constant (ms) 15.6 ± 3.2 (10) 15.6 (ms) Data Table
Neostriatum medium spiny neuron resting membrane potential (mV) -80.2 ± 1.3 (18) -80.2 (mV) Data Table
Neostriatum medium spiny neuron resting membrane potential (mV) -81.0 ± 1.7 (10) -81.0 (mV) Data Table
Neostriatum medium spiny neuron rheobase (nA) 0.7 ± 0.07 (7) 700.0 (pA) Data Table
Neostriatum medium spiny neuron rheobase (nA) 0.51 ± 0.04 (12) 510.0 (pA) Data Table
Neostriatum medium spiny neuron spike amplitude (mV) 60.8 ± 1.5 (13) 60.8 (mV) Data Table
Neostriatum medium spiny neuron spike amplitude (mV) 64.3 ± 3.1 (8) 64.3 (mV) Data Table
Neostriatum medium spiny neuron spike half-width (ms) 0.85 ± 0.03 (8) 0.85 (ms) Data Table
Neostriatum medium spiny neuron spike half-width (ms) 0.77 ± 0.03 (14) 0.77 (ms) Data Table
Neostriatum medium spiny neuron spike max decay slope (mV/ms) -85.5 ± 5.6 (8) 85.5 (mV/ms) Data Table
Neostriatum medium spiny neuron spike max decay slope (mV/ms) -98.1 ± 3.4 (13) 98.1 (mV/ms) Data Table
Neostriatum medium spiny neuron spike max rise slope (mV/ms) 248.9 ± 19.7 (8) 248.9 (mV/ms) Data Table
Neostriatum medium spiny neuron spike max rise slope (mV/ms) 228.5 ± 12.9 (13) 228.5 (mV/ms) Data Table
Neostriatum medium spiny neuron spike threshold (mV) -48.9 ± 2.2 (12) -48.9 (mV) Data Table
Neostriatum medium spiny neuron spike threshold (mV) -43.9 ± 6.1 (8) -43.9 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
RecTemp 31.0 - 32.0
AnimalAge 37.0 - 42.0
PrepType in vitro
ElectrodeType Sharp
Species Mice
ExternalSolution 5.0
JxnPotential Unreported
InternalSolution 5.0
Strain Mice, Transgenic
internal_0_K 3005.0
internal_0_Cl 5.0
external_0_Mg 2.0
external_0_Na 151.25
external_0_K 5.0
external_0_Cl 133.0
external_0_Ca 2.0
external_0_glucose 10.0
external_0_picro 0.05

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
947 Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice. Klapstein GJ; Fisher RS; Zanjani H; Cepeda C; Jokel ES; Chesselet MF; Levine MS J. Neurophysiol. 2001 False 10 Shreejoy Tripathy, James liu, Ryan Sefidpour, Athanasios Kritharis, 3
948 Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice. Klapstein GJ; Fisher RS; Zanjani H; Cepeda C; Jokel ES; Chesselet MF; Levine MS J. Neurophysiol. 2001 False 0 None