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Article: Long-term K+ channel-mediated dampening of dopamine neuron excitability by the antipsychotic drug haloperidol.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Hahn J; Tse TE; Levitan ES J. Neurosci., 2003
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Ventral tegmental area dopamine neuron | midbrain dopaminergic neuron | AHP amplitude (mV) | -56.2 ± 1.5 (5) | -- | Data Table |
| Ventral tegmental area dopamine neuron | midbrain dopaminergic neuron | spike half-width (msec) | 3.2 ± 1.4 (5) | 3.2 (ms) | Data Table |
| Ventral tegmental area dopamine neuron | midbrain dopaminergic neuron | spike peak (mV) | 33.1 ± 3.1 (5) | 33.1 (mV) | Data Table |
| Ventral tegmental area dopamine neuron | midbrain dopaminergic neuron | spike threshold (mV) | -44.5 ± 0.9 (5) | -44.5 (mV) | Data Table |
Metadata values
| Experimental condition | Value |
|---|---|
| Species | Rats |
| ElectrodeType | Patch-clamp |
| Strain | Sprague-Dawley |
| InternalSolution | 5.0 |
| ExternalSolution | 5.0 |
| JxnPotential | Unreported |
| PrepType | in vitro |
| AnimalAge | 11.0 - 12.0 |
| RecTemp | 20.0 - 24.0 |
| internal_0_pH | 7.4 |
| internal_0_Mg | 4.0 |
| internal_0_K | 130.0 |
| internal_0_ATP | 2.0 |
| internal_0_EGTA | 10.0 |
| internal_0_HEPES | 10.0 |
| internal_0_Cl | 140.0 |
| internal_0_Ca | 1.0 |
| external_0_pH | 7.4 |
| external_0_Mg | 1.0 |
| external_0_Na | 150.0 |
| external_0_K | 4.0 |
| external_0_HEPES | 10.0 |
| external_0_Cl | 160.0 |
| external_0_Ca | 2.0 |
| external_0_glucose | 10.0 |
Data table listing
| Data Table | Article Title | Authors | Journal | Year | Table needs expert? | Ephys table mentions | Curated by | Times validated |
|---|---|---|---|---|---|---|---|---|
| 2662 | Long-term K+ channel-mediated dampening of dopamine neuron excitability by the antipsychotic drug haloperidol. | Hahn J; Tse TE; Levitan ES | J. Neurosci. | 2003 | False | 4 | Shreejoy Tripathy, Brenna Li, Athanasios Kritharis, Nathalie Binnion, Patrick Savage, | 2 |