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Article: Increased gabaergic input to ventral tegmental area dopaminergic neurons associated with decreased cocaine reinforcement in mu-opioid receptor knockout mice.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Mathon DS; Lesscher HM; Gerrits MA; Kamal A; Pintar JE; Schuller AG; Spruijt BM; Burbach JP; Smidt MP; van Ree JM; Ramakers GM Neuroscience, 2005
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Other | Ventral tegmental area GABAergic neurons | AHP amplitude (mV) | -20.74 ± 2.07 (26) | 20.74 (mV) | Data Table |
| Other | Ventral tegmental area GABAergic neurons | spike amplitude (mV) | 74.61 ± 1.63 (26) | 74.61 (mV) | Data Table |
| Other | Ventral tegmental area GABAergic neurons | spike half-width (ms) | 2.58 ± 0.15 (26) | 2.58 (ms) | Data Table |
| Other | Ventral tegmental area GABAergic neurons | spike threshold (mV) | -47.37 ± 1.7 (26) | -47.37 (mV) | Data Table |
| Ventral tegmental area dopamine neuron | AHP amplitude (mV) | -28.82 ± 1.29 (49) | 28.82 (mV) | Data Table | |
| Ventral tegmental area dopamine neuron | spike amplitude (mV) | 67.13 ± 1.92 (49) | 67.13 (mV) | Data Table | |
| Ventral tegmental area dopamine neuron | spike half-width (ms) | 4.27 ± 0.2 (49) | 4.27 (ms) | Data Table | |
| Ventral tegmental area dopamine neuron | spike threshold (mV) | -40.41 ± 1.12 (49) | -40.41 (mV) | Data Table |
Metadata values
| Experimental condition | Value |
|---|---|
| Species | Mice |
| ElectrodeType | Patch-clamp |
| PrepType | in vitro |
| RecTemp | 20.0 - 24.0 |
| AnimalAge | 10.0 - 17.0 |
| ExternalSolution | 5.0 |
| JxnPotential | Corrected |
| JxnOffset | 16.1 |
| InternalSolution | 5.0 |
| Strain | C57BL |
| internal_0_pH | 7.4 |
| internal_0_Na | 2.4 |
| internal_0_K | 155.0 |
| internal_0_GTP | 0.4 |
| internal_0_ATP | 2.0 |
| internal_0_EGTA | 1.0 |
| internal_0_HEPES | 10.0 |
| external_0_Mg | 1.3 |
| external_0_Na | 144.0 |
| external_0_K | 4.5 |
| external_0_Cl | 132.3 |
| external_0_Ca | 2.5 |
| external_0_glucose | 10.0 |
Data table listing
| Data Table | Article Title | Authors | Journal | Year | Table needs expert? | Ephys table mentions | Curated by | Times validated |
|---|---|---|---|---|---|---|---|---|
| 21658 | Increased gabaergic input to ventral tegmental area dopaminergic neurons associated with decreased cocaine reinforcement in mu-opioid receptor knockout mice. | Mathon DS; Lesscher HM; Gerrits MA; Kamal A; Pintar JE; Schuller AG; Spruijt BM; Burbach JP; Smidt MP; van Ree JM; Ramakers GM | Neuroscience | 2005 | False | 4 | Nathalie Binnion, Brenna Li, Athanasios Kritharis, | 2 |
| 21657 | Increased gabaergic input to ventral tegmental area dopaminergic neurons associated with decreased cocaine reinforcement in mu-opioid receptor knockout mice. | Mathon DS; Lesscher HM; Gerrits MA; Kamal A; Pintar JE; Schuller AG; Spruijt BM; Burbach JP; Smidt MP; van Ree JM; Ramakers GM | Neuroscience | 2005 | False | 0 | None |