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Article: Diversity of layer 5 projection neurons in the mouse motor cortex.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Oswald MJ; Tantirigama ML; Sonntag I; Hughes SM; Empson RM
Front Cell Neurosci, 2013

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticocortical pyramidal neuron adaptation ratio (other) 2.53 ± 0.09 (25) 2.53 (None) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticothalamic thick tufted pyramidal neuron adaptation ratio (other) 4.33 ± 0.14 (23) 4.33 (None) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticostriatal pyramidal neuron adaptation ratio (other) 2.45 ± 0.11 (25) 2.45 (None) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticospinal thick tufted pyramidal neuron adaptation ratio (other) 3.56 ± 0.56 (26) 3.56 (None) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticocortical pyramidal neuron AHP amplitude (mV) -3.2 (25) 3.2 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticothalamic thick tufted pyramidal neuron AHP amplitude (mV) -8.5 (23) 8.5 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticostriatal pyramidal neuron AHP amplitude (mV) -3.8 (25) 3.8 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticospinal thick tufted pyramidal neuron AHP amplitude (mV) -7.9 (26) 7.9 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticostriatal pyramidal neuron FI slope (Hz/pA) 0.088 ± 0.007 (25) 88.0 (Hz/nA) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticospinal thick tufted pyramidal neuron FI slope (Hz/pA) 0.082 ± 0.002 (26) 82.0 (Hz/nA) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticocortical pyramidal neuron FI slope (Hz/pA) 0.082 ± 0.005 (25) 82.0 (Hz/nA) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticothalamic thick tufted pyramidal neuron FI slope (Hz/pA) 0.069 ± 0.002 (23) 69.0 (Hz/nA) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticospinal thick tufted pyramidal neuron input resistance (MΩ) 111.0 (26) 111.0 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticocortical pyramidal neuron input resistance (MΩ) 209.0 (25) 209.0 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticothalamic thick tufted pyramidal neuron input resistance (MΩ) 85.0 (23) 85.0 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticostriatal pyramidal neuron input resistance (MΩ) 221.0 (25) 221.0 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticostriatal pyramidal neuron maximum firing rate (Hz) 29.2 (25) 29.2 (Hz) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticospinal thick tufted pyramidal neuron maximum firing rate (Hz) 34.1 (26) 34.1 (Hz) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticocortical pyramidal neuron maximum firing rate (Hz) 25.2 (25) 25.2 (Hz) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticothalamic thick tufted pyramidal neuron maximum firing rate (Hz) 26.0 (23) 26.0 (Hz) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticocortical pyramidal neuron membrane time constant (ms) 34.4 (25) 34.4 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticothalamic thick tufted pyramidal neuron membrane time constant (ms) 20.5 (23) 20.5 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticostriatal pyramidal neuron membrane time constant (ms) 33.0 (25) 33.0 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticospinal thick tufted pyramidal neuron membrane time constant (ms) 27.7 (26) 27.7 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticothalamic thick tufted pyramidal neuron resting membrane potential (mV) -68.0 (23) -68.0 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticospinal thick tufted pyramidal neuron resting membrane potential (mV) -64.9 (26) -64.9 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticostriatal pyramidal neuron resting membrane potential (mV) -67.9 (25) -67.9 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticocortical pyramidal neuron resting membrane potential (mV) -69.9 (25) -69.9 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticospinal thick tufted pyramidal neuron sag ratio 0.3 (26) 0.3 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticocortical pyramidal neuron sag ratio 0.17 (25) 0.17 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticothalamic thick tufted pyramidal neuron sag ratio 0.49 (23) 0.49 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticostriatal pyramidal neuron sag ratio 0.1 (25) 0.1 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticocortical pyramidal neuron medium AHP amplitude (mV) -15.8 (25) 15.8 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticothalamic thick tufted pyramidal neuron medium AHP amplitude (mV) -16.3 (23) 16.3 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticostriatal pyramidal neuron medium AHP amplitude (mV) -16.0 (25) 16.0 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticospinal thick tufted pyramidal neuron medium AHP amplitude (mV) -12.3 (26) 12.3 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticothalamic thick tufted pyramidal neuron spike amplitude (mV) 82.9 (23) 82.9 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticocortical pyramidal neuron spike amplitude (mV) 81.3 (25) 81.3 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticospinal thick tufted pyramidal neuron spike amplitude (mV) 79.6 (26) 79.6 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticostriatal pyramidal neuron spike amplitude (mV) 68.1 (25) 68.1 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticocortical pyramidal neuron spike decay time (V/s) -45.7 ± 1.8 (25) -- Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticothalamic thick tufted pyramidal neuron spike decay time (V/s) -77.1 ± 3.1 (23) -- Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticostriatal pyramidal neuron spike decay time (V/s) -42.5 ± 1.9 (25) -- Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticospinal thick tufted pyramidal neuron spike decay time (V/s) -71.1 ± 2.3 (26) -- Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticocortical pyramidal neuron spike half-width (ms) 1.58 ± 0.05 (25) 1.58 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticothalamic thick tufted pyramidal neuron spike half-width (ms) 1.1 ± 0.04 (23) 1.1 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticostriatal pyramidal neuron spike half-width (ms) 1.55 ± 0.05 (25) 1.55 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticospinal thick tufted pyramidal neuron spike half-width (ms) 1.2 ± 0.04 (26) 1.2 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticospinal thick tufted pyramidal neuron spike rise time (V/s) 222.0 ± 8.0 (26) -- Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticocortical pyramidal neuron spike rise time (V/s) 221.0 ± 10.0 (25) -- Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticothalamic thick tufted pyramidal neuron spike rise time (V/s) 272.0 ± 9.0 (23) -- Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticostriatal pyramidal neuron spike rise time (V/s) 159.0 ± 8.0 (25) -- Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticocortical pyramidal neuron spike threshold (mV) -36.3 ± 0.5 (25) -36.3 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticothalamic thick tufted pyramidal neuron spike threshold (mV) -39.5 ± 0.8 (23) -39.5 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticospinal thick tufted pyramidal neuron spike threshold (mV) -41.4 ± 1.0 (26) -41.4 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5 corticostriatal pyramidal neuron spike threshold (mV) -34.9 ± 0.7 (25) -34.9 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
ElectrodeType Patch-clamp
PrepType in vitro
AnimalAge 23.0 - 32.0
ExternalSolution 5.0
InternalSolution 5.0
Species Mice
Strain Other
JxnPotential Not corrected
RecTemp 26.0
internal_0_pH 7.3
internal_0_Mg 4.0
internal_0_Na 10.6
internal_0_K 120.0
internal_0_GTP 0.3
internal_0_ATP 4.0
internal_0_HEPES 10.0
internal_0_Cl 10.0
external_0_Mg 2.0
external_0_Na 158.0
external_0_K 3.0
external_0_Cl 133.0
external_0_Ca 2.0
external_0_glucose 15.0
external_0_CNQX 10.0
external_0_DAPV 50.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
27538 Diversity of layer 5 projection neurons in the mouse motor cortex. Oswald MJ; Tantirigama ML; Sonntag I; Hughes SM; Empson RM Front Cell Neurosci 2013 False 10 0
27536 Diversity of layer 5 projection neurons in the mouse motor cortex. Oswald MJ; Tantirigama ML; Sonntag I; Hughes SM; Empson RM Front Cell Neurosci 2013 False 8 Shreejoy Tripathy, Nathalie Binnion, Brenna Li, 5
27537 Diversity of layer 5 projection neurons in the mouse motor cortex. Oswald MJ; Tantirigama ML; Sonntag I; Hughes SM; Empson RM Front Cell Neurosci 2013 False 6 Shreejoy Tripathy, Nathalie Binnion, Brenna Li, 5
27535 Diversity of layer 5 projection neurons in the mouse motor cortex. Oswald MJ; Tantirigama ML; Sonntag I; Hughes SM; Empson RM Front Cell Neurosci 2013 False 0 None