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Article: Excitability and synaptic alterations in the cerebellum of APP/PS1 mice.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Hoxha E; Boda E; Montarolo F; Parolisi R; Tempia F
PLoS ONE, 2012

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Cerebellum Purkinje cell AHP amplitude (mV) 14.4 ± 1.8 (14) 14.4 (mV) Data Table
Cerebellum Purkinje cell AHP amplitude (mV) 21.5 ± 2.3 (8) 21.5 (mV) Data Table
Cerebellum Purkinje cell firing frequency (Hz) 43.9 ± 20.0 (8) 43.9 (Hz) Data Table
Cerebellum Purkinje cell firing frequency (Hz) 36.8 ± 5.6 (14) 36.8 (Hz) Data Table
Cerebellum Purkinje cell first spike latency (ms) 3.9 ± 0.8 (14) 3.9 (ms) Data Table
Cerebellum Purkinje cell first spike latency (ms) 12.2 ± 3.7 (8) 12.2 (ms) Data Table
Cerebellum Purkinje cell input resistance (MΩ) 112.9 ± 4.7 (14) 112.9 (MΩ) Data Table
Cerebellum Purkinje cell input resistance (MΩ) 88.1 ± 4.9 (8) 88.1 (MΩ) Data Table
Cerebellum Purkinje cell sag amplitude (mV) 41.3 ± 2.5 (14) 41.3 (mV) Data Table
Cerebellum Purkinje cell sag amplitude (mV) 47.6 ± 3.0 (8) 47.6 (mV) Data Table
Cerebellum Purkinje cell spike amplitude (mV) 88.6 ± 1.6 (14) 88.6 (mV) Data Table
Cerebellum Purkinje cell spike amplitude (mV) 82.7 ± 4.1 (8) 82.7 (mV) Data Table
Cerebellum Purkinje cell spike threshold (mV) 43.3 ± 1.9 (14) -43.3 (mV) Data Table
Cerebellum Purkinje cell spike threshold (mV) 52.0 ± 3.1 (8) -52.0 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
Species Mice
ElectrodeType Patch-clamp
Strain Mice, Transgenic
RecTemp 22.0 - 25.0
PrepType in vitro
InternalSolution 5.0
internal_1_pH 7.3
internal_1_Mg 4.0
internal_1_Na 9.2
internal_1_Cl 8.0
internal_1_K 140.0
ExternalSolution 5.0
JxnPotential Unreported
internal_0_pH 7.3
internal_0_Mg 4.0
internal_0_Na 9.2
internal_0_GTP 0.4
internal_0_ATP 4.0
internal_0_EGTA 10.0
internal_0_HEPES 10.0
internal_0_Cl 138.0
internal_0_Cs 130.0
external_0_pH 7.4
external_0_Mg 1.0
external_0_Na 152.25
external_0_K 2.5
external_0_Cl 133.5
external_0_Ca 2.0
external_0_glucose 20.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
39318 Excitability and synaptic alterations in the cerebellum of APP/PS1 mice. Hoxha E; Boda E; Montarolo F; Parolisi R; Tempia F PLoS ONE 2012 False 7 Shreejoy Tripathy, Ryan Sefidpour, 1
39319 Excitability and synaptic alterations in the cerebellum of APP/PS1 mice. Hoxha E; Boda E; Montarolo F; Parolisi R; Tempia F PLoS ONE 2012 False 0 None