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Article: Aging-Related Hyperexcitability in CA3 Pyramidal Neurons Is Mediated by Enhanced A-Type K+ Channel Function and Expression.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Simkin D; Hattori S; Ybarra N; Musial TF; Buss EW; Richter H; Oh MM; Nicholson DA; Disterhoft JF
J. Neurosci., 2015

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA3 pyramidal cell access resistance (mΩ) 21.56 ± 0.77 (52) 21.56 (MΩ) Data Table
Hippocampus CA3 pyramidal cell access resistance (mΩ) 21.33 ± 1.08 (44) 21.33 (MΩ) Data Table
Hippocampus CA3 pyramidal cell input resistance (mΩ) 85.01 ± 4.41 (52) 85.01 (MΩ) Data Table
Hippocampus CA3 pyramidal cell input resistance (mΩ) 79.99 ± 4.73 (44) 79.99 (MΩ) Data Table
Hippocampus CA3 pyramidal cell resting membrane potential (mV) -67.56 ± 1.02 (44) -67.56 (mV) Data Table
Hippocampus CA3 pyramidal cell resting membrane potential (mV) -68.97 ± 0.75 (52) -68.97 (mV) Data Table
Hippocampus CA3 pyramidal cell sag amplitude (mV) -2.28 ± 0.13 (52) -2.28 (mV) Data Table
Hippocampus CA3 pyramidal cell sag amplitude (mV) -2.32 ± 0.17 (44) -2.32 (mV) Data Table
Hippocampus CA3 pyramidal cell spike amplitude from resting (mV) 83.74 ± 1.1 (31) 83.74 (mV) Data Table
Hippocampus CA3 pyramidal cell spike amplitude from resting (mV) 86.11 ± 1.19 (29) 86.11 (mV) Data Table
Hippocampus CA3 pyramidal cell spike threshold (mV) -47.89 ± 0.87 (29) -47.89 (mV) Data Table
Hippocampus CA3 pyramidal cell spike threshold (mV) -48.26 ± 0.86 (31) -48.26 (mV) Data Table
Hippocampus CA3 pyramidal cell fast AHP amplitude (mV) -53.76 ± 0.74 (28) -- Data Table
Hippocampus CA3 pyramidal cell fast AHP amplitude (mV) -50.94 ± 0.63 (42) -- Data Table
Hippocampus CA3 pyramidal cell spike half-width (ms) 1.09 ± 0.02 (28) 1.09 (ms) Data Table
Hippocampus CA3 pyramidal cell spike half-width (ms) 1.16 ± 0.02 (43) 1.16 (ms) Data Table

Report miscurated data

Metadata values

Experimental condition Value
Species Rats
ElectrodeType Patch-clamp
PrepType in vitro
InternalSolution 5.0
ExternalSolution 5.0
JxnPotential Unreported
RecTemp 32.0 - 34.0
Strain Fischer 344
internal_0_pH 7.3
internal_0_Mg 4.0
internal_0_Na 21.2
internal_0_K 130.0
internal_0_GTP 0.4
internal_0_ATP 4.0
internal_0_HEPES 10.0
internal_0_Cl 10.0
external_0_pH 7.4
external_0_Mg 2.0
external_0_Na 152.25
external_0_K 2.5
external_0_Cl 132.3
external_0_Ca 2.4
external_0_glucose 25.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
47341 Aging-Related Hyperexcitability in CA3 Pyramidal Neurons Is Mediated by Enhanced A-Type K+ Channel Function and Expression. Simkin D; Hattori S; Ybarra N; Musial TF; Buss EW; Richter H; Oh MM; Nicholson DA; Disterhoft JF J. Neurosci. 2015 False 6 Shreejoy Tripathy, Brenna Li, Ryan Sefidpour, Athanasios Kritharis, 2
47343 Aging-Related Hyperexcitability in CA3 Pyramidal Neurons Is Mediated by Enhanced A-Type K+ Channel Function and Expression. Simkin D; Hattori S; Ybarra N; Musial TF; Buss EW; Richter H; Oh MM; Nicholson DA; Disterhoft JF J. Neurosci. 2015 False 2 Brenna Li, Ryan Sefidpour, 1
47342 Aging-Related Hyperexcitability in CA3 Pyramidal Neurons Is Mediated by Enhanced A-Type K+ Channel Function and Expression. Simkin D; Hattori S; Ybarra N; Musial TF; Buss EW; Richter H; Oh MM; Nicholson DA; Disterhoft JF J. Neurosci. 2015 False 1 0