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Article: Hippocampal function is compromised in an animal model of multiple sclerosis.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Novkovic T; Shchyglo O; Gold R; Manahan-Vaughan D
Neuroscience, 2015

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell Hippocampus CA1 stratum radiatum pyramidal immunized with ovalbumin neurons adaptation ratio (last/first ISI) 1.88 ± 0.35 1.88 (ratio) Data Table
Hippocampus CA1 pyramidal cell Hippocampus CA1 stratum radiatum pyramidal immunized with ovalbumin neurons adaptation ratio (last/first ISI) 2.0 ± 0.18 2.0 (ratio) Data Table
Hippocampus CA1 pyramidal cell Hippocampus CA1 stratum radiatum pyramidal immunized with ovalbumin neurons input resistance (MΩ) 140.9 ± 6.5 140.9 (MΩ) Data Table
Hippocampus CA1 pyramidal cell Hippocampus CA1 stratum radiatum pyramidal immunized with ovalbumin neurons input resistance (MΩ) 145.5 ± 10.4 145.5 (MΩ) Data Table
Hippocampus CA1 pyramidal cell Hippocampus CA1 stratum radiatum pyramidal immunized with ovalbumin neurons membrane time constant (ms) 9.9 ± 0.8 9.9 (ms) Data Table
Hippocampus CA1 pyramidal cell Hippocampus CA1 stratum radiatum pyramidal immunized with ovalbumin neurons membrane time constant (ms) 9.6 ± 1.4 9.6 (ms) Data Table
Hippocampus CA1 pyramidal cell Hippocampus CA1 stratum radiatum pyramidal immunized with ovalbumin neurons resting membrane potential (mV) -65.75 ± 1.1 -65.75 (mV) Data Table
Hippocampus CA1 pyramidal cell Hippocampus CA1 stratum radiatum pyramidal immunized with ovalbumin neurons resting membrane potential (mV) -64.67 ± 1.0 -64.67 (mV) Data Table
Hippocampus CA1 pyramidal cell Hippocampus CA1 stratum radiatum pyramidal immunized with ovalbumin neurons rheobase (pA) 111.2 ± 7.4 111.2 (pA) Data Table
Hippocampus CA1 pyramidal cell Hippocampus CA1 stratum radiatum pyramidal immunized with ovalbumin neurons rheobase (pA) 108.9 ± 8.6 108.9 (pA) Data Table
Hippocampus CA1 pyramidal cell Hippocampus CA1 stratum radiatum pyramidal immunized with ovalbumin neurons spike amplitude (mV) 104.8 ± 1.1 104.8 (mV) Data Table
Hippocampus CA1 pyramidal cell Hippocampus CA1 stratum radiatum pyramidal immunized with ovalbumin neurons spike amplitude (mV) 103.5 ± 0.7 103.5 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
ElectrodeType Patch-clamp
RecTemp 23.0
InternalSolution 5.0
ExternalSolution 5.0
Species Mice
Strain C57BL
PrepType in vitro
JxnPotential Unreported
internal_0_pH 7.2
internal_0_Mg 1.0
internal_0_Na 2.0
internal_0_K 130.0
internal_0_ATP 2.0
internal_0_EGTA 5.0
internal_0_HEPES 10.0
internal_0_Cl 34.5
external_0_pH 7.4
external_0_Mg 1.3
external_0_Na 149.6
external_0_K 6.1
external_0_Cl 133.9
external_0_Ca 2.5
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
47576 Hippocampal function is compromised in an animal model of multiple sclerosis. Novkovic T; Shchyglo O; Gold R; Manahan-Vaughan D Neuroscience 2015 False 6 Shreejoy Tripathy, Nathalie Binnion, Brenna Li, 2