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Article: Altered intrinsic excitability of hippocampal CA1 pyramidal neurons in aged PDAPP mice.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Tamagnini F; Novelia J; Kerrigan TL; Brown JT; Tsaneva-Atanasova K; Randall AD
Front Cell Neurosci, 2015

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell cell capacitance (pF) 177.2 (27) 177.2 (pF) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 100.2 (27) 100.2 (MΩ) Data Table
Hippocampus CA1 pyramidal cell membrane time constant (ms) 16.2 (27) 16.2 (ms) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -76.7 (27) -76.7 (mV) Data Table
Hippocampus CA1 pyramidal cell sag ratio 20.2 (27) 0.202 (ratio) Data Table
Hippocampus CA1 pyramidal cell AHP amplitude (mV) 2.46 (27) 2.46 (mV) Data Table
Hippocampus CA1 pyramidal cell spike half-width (ms) 0.83 (27) 0.83 (ms) Data Table
Hippocampus CA1 pyramidal cell spike max rise slope 371.43 (27) 371.43 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell spike peak (mV) 25.05 (27) 25.05 (mV) Data Table
Hippocampus CA1 pyramidal cell spike threshold (mV) -58.64 (27) -58.64 (mV) Data Table

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Metadata values

Experimental condition Value
ElectrodeType Patch-clamp
RecTemp 33.0 ± 1.0
PrepType in vitro
JxnPotential Corrected
InternalSolution 5.0
ExternalSolution 5.0
Species Mice
AnimalAge 600.0 - 690.0
JxnOffset 15.0
Strain C57BL
internal_0_pH 7.3
internal_0_Mg 4.0
internal_0_Na 5.3
internal_0_K 145.0
internal_0_GTP 0.3
internal_0_ATP 4.0
internal_0_EGTA 0.2
internal_0_HEPES 10.0
internal_0_Cl 5.0
external_0_Mg 1.0
external_0_Na 149.25
external_0_K 3.0
external_0_Cl 131.0
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
48900 Altered intrinsic excitability of hippocampal CA1 pyramidal neurons in aged PDAPP mice. Tamagnini F; Novelia J; Kerrigan TL; Brown JT; Tsaneva-Atanasova K; Randall AD Front Cell Neurosci 2015 False 5 James liu, Ryan Sefidpour, 1
48902 Altered intrinsic excitability of hippocampal CA1 pyramidal neurons in aged PDAPP mice. Tamagnini F; Novelia J; Kerrigan TL; Brown JT; Tsaneva-Atanasova K; Randall AD Front Cell Neurosci 2015 False 5 James liu, Ryan Sefidpour, 2
48901 Altered intrinsic excitability of hippocampal CA1 pyramidal neurons in aged PDAPP mice. Tamagnini F; Novelia J; Kerrigan TL; Brown JT; Tsaneva-Atanasova K; Randall AD Front Cell Neurosci 2015 False 0 None