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Article: Pacemaker rate and depolarization block in nigral dopamine neurons: a somatic sodium channel balancing act.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Tucker KR; Huertas MA; Horn JP; Canavier CC; Levitan ES J. Neurosci., 2012
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Substantia nigra pars compacta dopaminergic cell | AHP voltage (mV) | -56.5 ± 1.3 (9) | -56.5 (mV) | Data Table | |
| Substantia nigra pars compacta dopaminergic cell | spike max rise slope (V/s) | 125.7 ± 9.0 (9) | 125.7 (mV/ms) | Data Table | |
| Substantia nigra pars compacta dopaminergic cell | spike peak (mV) | 26.5 ± 1.4 (9) | 26.5 (mV) | Data Table | |
| Substantia nigra pars compacta dopaminergic cell | spike threshold (mV) | -40.8 ± 1.8 (9) | -40.8 (mV) | Data Table |
Metadata values
| Experimental condition | Value |
|---|---|
| Species | Rats |
| ElectrodeType | Patch-clamp |
| Strain | Rats, Sprague-Dawley |
| RecTemp | 25.0 |
| PrepType | in vitro |
| ExternalSolution | 5.0 |
| InternalSolution | 5.0 |
| JxnPotential | Unreported |
| internal_0_pH | 7.3 |
| internal_0_Mg | 2.0 |
| internal_0_Na | 2.4 |
| internal_0_K | 140.0 |
| internal_0_ATP | 1.2 |
| internal_0_EGTA | 0.1 |
| internal_0_HEPES | 10.0 |
| internal_0_Cl | 24.0 |
| external_0_pH | 7.4 |
| external_0_Mg | 1.2 |
| external_0_Na | 150.95 |
| external_0_K | 4.0 |
| external_0_Cl | 132.9 |
| external_0_Ca | 2.45 |
| external_0_glucose | 11.0 |
Data table listing
| Data Table | Article Title | Authors | Journal | Year | Table needs expert? | Ephys table mentions | Curated by | Times validated |
|---|---|---|---|---|---|---|---|---|
| 47127 | Pacemaker rate and depolarization block in nigral dopamine neurons: a somatic sodium channel balancing act. | Tucker KR; Huertas MA; Horn JP; Canavier CC; Levitan ES | J. Neurosci. | 2012 | False | 4 | Shreejoy Tripathy, Kerrie Tsigounis, Brenna Li, | 2 |
| 47126 | Pacemaker rate and depolarization block in nigral dopamine neurons: a somatic sodium channel balancing act. | Tucker KR; Huertas MA; Horn JP; Canavier CC; Levitan ES | J. Neurosci. | 2012 | False | 0 | None |