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Article: Differential changes of potassium currents in CA1 pyramidal neurons after transient forebrain ischemia.

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Chi XX; Xu ZC
J. Neurophysiol., 2000


Table 3.

Kinetics of transient potassium current before and after ischemia

Control 6–8 h 12–14 h 18–20 h 36 h
V 1/2 (Act), mV −6.31 ± 1.48 −29.67 ± 1.53* −27.03 ± 1.24* −17.55 ± 1.54 −17.49 ± 0.85
V c (Act), mV 14.63 ± 1.20 14.67 ± 1.31 12.34 ± 1.06 15.08 ± 1.27 12.73 ± 0.71
V 1/2 (Inact), mV −59.58 ± 1.02 −65.50 ± 0.90 −63.32 ± 0.76 −61.88 ± 0.67 −72.82 ± 0.65
V c (Inact), mV 13.23 ± 0.92 15.49 ± 0.81 14.75 ± 0.69 11.10 ± 0.59 14.03 ± 0.59
  • V 1/2, the potential of half-maximal activation or inactivation; V c, proportional to the slope at V 1/2; * P < 0.05.


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